4FSJ
 
 | | Crystal structure of the virus like particle of Flock House virus | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Speir, J.A, Chen, Z, Reddy, V.S, Johnson, J.E. | | 登録日 | 2012-06-27 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
to be published, 2012
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4GEE
 | | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. | | 分子名称: | (1R,5S,6s)-3-[5-chloro-6-ethyl-2-(pyrimidin-5-yloxy)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-amine, DNA gyrase subunit B, GLYCEROL | | 著者 | Bensen, D.C, Chen, Z, Tari, L.W. | | 登録日 | 2012-08-01 | | 公開日 | 2013-02-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Bioorg.Med.Chem.Lett., 23, 2013
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4FTS
 | | Crystal structure of the N363T mutant of the Flock House virus capsid | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Speir, J.A, Chen, Z, Reddy, V.S, Johnson, J.E. | | 登録日 | 2012-06-28 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
to be published, 2012
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6A58
 | | Structure of histone demethylase REF6 | | 分子名称: | Lysine-specific demethylase REF6, ZINC ION | | 著者 | Tian, Z, Chen, Z. | | 登録日 | 2018-06-22 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms.
Cell Discov, 6, 2020
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6A57
 | | Structure of histone demethylase REF6 complexed with DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*TP*CP*TP*CP*TP*GP*TP*TP*TP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*AP*AP*A)-3'), GLYCEROL, ... | | 著者 | Tian, Z, Chen, Z. | | 登録日 | 2018-06-22 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms.
Cell Discov, 6, 2020
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3LU9
 | | Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Proteinase-activated receptor 1, ... | | 著者 | Gandhi, P.S, Chen, Z, Di Cera, E. | | 登録日 | 2010-02-17 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1.
J.Biol.Chem., 285, 2010
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3HK3
 | | Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit) | | 分子名称: | Thrombin heavy chain, Thrombin light chain | | 著者 | Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E. | | 登録日 | 2009-05-22 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
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3HK6
 | | Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit) | | 分子名称: | Thrombin heavy chain, Thrombin light chain | | 著者 | Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E. | | 登録日 | 2009-05-22 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
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3HKI
 | | Crystal structure of murine thrombin mutant W215A/E217A in complex with the extracellular fragment of human PAR1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 1, Thrombin heavy chain, ... | | 著者 | Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E. | | 登録日 | 2009-05-23 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
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3HKJ
 | | Crystal structure of human thrombin mutant W215A/E217A in complex with the extracellular fragment of human PAR1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 1, Thrombin heavy chain, ... | | 著者 | Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E. | | 登録日 | 2009-05-23 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
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3OQU
 | | Crystal structure of native abscisic acid receptor PYL9 with ABA | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL9 | | 著者 | Zhang, X, Zhang, Q, Chen, Z. | | 登録日 | 2010-09-04 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural Insights into the Abscisic Acid Stereospecificity by the ABA Receptors PYR/PYL/RCAR
Plos One, 8, 2013
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1T2L
 | | Three Crystal Structures of Human Coactosin-like Protein | | 分子名称: | Coactosin-like protein | | 著者 | Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W. | | 登録日 | 2004-04-22 | | 公開日 | 2004-11-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Human Coactosin-like Protein
J.Mol.Biol., 344, 2004
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3CX8
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3CX7
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3CX6
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3E6P
 | | Crystal structure of human meizothrombin desF1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-PHENYLALANYL-N-[(1S)-4-{[(Z)-AMINO(IMINO)METHYL]AMINO}-1-(CHLOROACETYL)BUTYL]-L-PROLINAMIDE, Prothrombin, ... | | 著者 | Papaconstantinou, M.E, Gandhi, P, Chen, Z, Bah, A, Di Cera, E. | | 登録日 | 2008-08-15 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Na(+) binding to meizothrombin desF1.
Cell.Mol.Life Sci., 65, 2008
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3QGN
 | | The allosteric E*-E equilibrium is a key property of the trypsin fold | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IODIDE ION, ... | | 著者 | Niu, W, Gohara, D, Chen, Z, Di Cera, E. | | 登録日 | 2011-01-24 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic and kinetic evidence of allostery in a trypsin-like protease.
Biochemistry, 50, 2011
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3GIC
 | | Structure of thrombin mutant delta(146-149e) in the free form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin heavy chain, Thrombin light chain | | 著者 | Bah, A, Carrell, C.J, Chen, Z, Gandhi, P.S, Di Cera, E. | | 登録日 | 2009-03-05 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Stabilization of the E* form turns thrombin into an anticoagulant.
J.Biol.Chem., 284, 2009
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3S7H
 | | Structure of thrombin mutant Y225P in the E* form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Prothrombin | | 著者 | Niu, W, Chen, Z, Gandhi, P, Vogt, A, Pozzi, N, Pele, L.A, Zapata, F, Di Cera, E. | | 登録日 | 2011-05-26 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease.
Biochemistry, 50, 2011
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3MVT
 | | Crystal structure of apo mADA at 2.2A resolution | | 分子名称: | Adenosine deaminase, CHLORIDE ION, GLYCEROL | | 著者 | Niu, W, Shu, Q, Chen, Z, Mathews, S, Di Cera, E, Frieden, C. | | 登録日 | 2010-05-04 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The role of Zn2+ on the structure and stability of murine adenosine deaminase.
J.Phys.Chem.B, 114, 2010
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2GP9
 | | Crystal structure of the slow form of thrombin in a self-inhibited conformation | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Prothrombin | | 著者 | Pineda, A, Chen, Z, Mathews, F.S, Di Cera, E. | | 登録日 | 2006-04-17 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structure of thrombin in a self-inhibited conformation.
J.Biol.Chem., 281, 2006
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4GQH
 | | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies | | 分子名称: | Capsid protein | | 著者 | Li, X.Y, Song, B.A, Hu, D.Y, Chen, X, Wang, Z.C, Zeng, M.J, Yu, D.D, Chen, Z, Jin, L.H, Yang, S. | | 登録日 | 2012-08-23 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies
To be Published
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3QDZ
 | | Crystal structure of the human thrombin mutant D102N in complex with the extracellular fragment of human PAR4. | | 分子名称: | Proteinase-activated receptor 4, Thrombin heavy chain, Thrombin light chain | | 著者 | Gandhi, P, Chen, Z, Appelbaum, E, Zapata, F, Di Cera, E. | | 登録日 | 2011-01-19 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of thrombin-protease-receptor interactions
IUBMB LIFE, 63, 2011
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4RAY
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3S7K
 | | Structure of thrombin mutant Y225P in the E form | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, POTASSIUM ION, Prothrombin | | 著者 | Niu, W, Chen, Z, Gandhi, P, Vogt, A, Pozzi, N, Pele, L.A, Zapata, F, Di Cera, E. | | 登録日 | 2011-05-26 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease.
Biochemistry, 50, 2011
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