2GP9
Crystal structure of the slow form of thrombin in a self-inhibited conformation
Summary for 2GP9
| Entry DOI | 10.2210/pdb2gp9/pdb |
| Related | 1SHH |
| Descriptor | Prothrombin, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
| Functional Keywords | serine protease, hydrolase |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted, extracellular space: P00734 P00734 |
| Total number of polymer chains | 2 |
| Total formula weight | 34114.07 |
| Authors | Pineda, A.,Chen, Z.,Mathews, F.S.,Di Cera, E. (deposition date: 2006-04-17, release date: 2006-09-12, Last modification date: 2023-08-30) |
| Primary citation | Pineda, A.O.,Chen, Z.W.,Bah, A.,Garvey, L.C.,Mathews, F.S.,Di Cera, E. Crystal structure of thrombin in a self-inhibited conformation. J.Biol.Chem., 281:32922-32928, 2006 Cited by PubMed: 16954215DOI: 10.1074/jbc.M605530200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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