3S7K
Structure of thrombin mutant Y225P in the E form
Summary for 3S7K
Entry DOI | 10.2210/pdb3s7k/pdb |
Related | 1shh 3S7H |
Descriptor | Prothrombin, POTASSIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total) |
Functional Keywords | serine protease, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 4 |
Total formula weight | 67741.66 |
Authors | Niu, W.,Chen, Z.,Gandhi, P.,Vogt, A.,Pozzi, N.,Pele, L.A.,Zapata, F.,Di Cera, E. (deposition date: 2011-05-26, release date: 2011-07-06, Last modification date: 2023-09-13) |
Primary citation | Niu, W.,Chen, Z.,Gandhi, P.S.,Vogt, A.D.,Pozzi, N.,Pelc, L.A.,Zapata, F.,Di Cera, E. Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease. Biochemistry, 50:6301-6307, 2011 Cited by PubMed: 21707111DOI: 10.1021/bi200878c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report