1SHH

Slow form of Thrombin Bound with PPACK

Summary for 1SHH

Entry DOI	10.2210/pdb1shh/pdb
Related	1SFQ 1SG8 1SGI
Related PRD ID	PRD_000020
Descriptor	thrombin, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	68710.45
Authors	Pineda, A.O.,Carrell, C.J.,Bush, L.A.,Prasad, S.,Caccia, S.,Chen, Z.W.,Mathews, F.S.,Di Cera, E. (deposition date: 2004-02-25, release date: 2004-06-08, Last modification date: 2024-03-13)
Primary citation	Pineda, A.O.,Carrell, C.J.,Bush, L.A.,Prasad, S.,Caccia, S.,Chen, Z.W.,Mathews, F.S.,Di Cera, E. Molecular dissection of na+ binding to thrombin. J.Biol.Chem., 279:31842-31853, 2004 Cited by PubMed: 15152000 DOI: 10.1074/jbc.M401756200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation