1SGI

Crystal structure of the anticoagulant slow form of thrombin

Summary for 1SGI

Entry DOI	10.2210/pdb1sgi/pdb
Related	1SFQ 1SG8 1SGI 1SHH
Descriptor	thrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	thrombin, allostery, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	68023.69
Authors	Pineda, A.O.,Carrell, C.J.,Bush, L.A.,Prasad, S.,Caccia, S.,Chen, Z.W.,Mathews, F.S.,Di Cera, E. (deposition date: 2004-02-23, release date: 2004-06-08, Last modification date: 2023-08-23)
Primary citation	Pineda, A.O.,Carrell, C.J.,Bush, L.A.,Prasad, S.,Caccia, S.,Chen, Z.W.,Mathews, F.S.,Di Cera, E. Molecular dissection of na+ binding to thrombin. J.Biol.Chem., 279:31842-31853, 2004 Cited by PubMed: 15152000 DOI: 10.1074/jbc.M401756200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation