1SFQ

Fast form of thrombin mutant R(77a)A bound to PPACK

Summary for 1SFQ
Related1SG8 1SGI 1SHH
Related PRD IDPRD_000020
Descriptorthrombin, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordsserine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight68977.64
Authors
Pineda, A.O.,Carrell, C.J.,Bush, L.A.,Prasad, S.,Caccia, S.,Chen, Z.W.,Mathews, F.S.,Di Cera, E. (deposition date: 2004-02-20, release date: 2004-06-08, Last modification date: 2020-07-29)
Primary citationBush, L.A.,Caccia, S.,Carrell, C.J.,Chen, Z.W.,Di Cera, E.,Mathews, F.S.,Pineda, A.O.,Prasad, S.
Molecular dissection of na+ binding to thrombin.
J.Biol.Chem., 279:31842-31853, 2004
PubMed: 15152000
DOI: 110.1074/jbc.M401756200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.91 Å)
Structure validation
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PDB entries from 2021-06-16