8EOI
| Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. | 登録日 | 2022-10-03 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | EMC chaperone-Ca V structure reveals an ion channel assembly intermediate. Nature, 619, 2023
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8EOG
| Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine | 分子名称: | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. | 登録日 | 2022-10-03 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | EMC chaperone-Ca V structure reveals an ion channel assembly intermediate. Nature, 619, 2023
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6L30
| Crystal structure of the epithelial cell transforming 2 (ECT2) | 分子名称: | Protein ECT2 | 著者 | Chen, Z.C, Chen, M.R, Pan, H, Sun, L.F, Shi, P. | 登録日 | 2019-10-07 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure and regulation of human epithelial cell transforming 2 protein. Proc.Natl.Acad.Sci.USA, 117, 2020
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8FD7
| Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin | 分子名称: | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Z, Mondal, A, Minor, D.L. | 登録日 | 2022-12-02 | 公開日 | 2023-03-22 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for Ca V alpha 2 delta :gabapentin binding. Nat.Struct.Mol.Biol., 30, 2023
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4XGA
| Crystal structure of BamB and BamA P3-5 complex from E.coli | 分子名称: | CALCIUM ION, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB | 著者 | Chen, Z, Zhan, L.H, Dong, C, Gao, Z.Q, Dong, Y.H. | 登録日 | 2014-12-30 | 公開日 | 2016-01-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the interaction of BamB with the POTRA3-4 domains of BamA. Acta Crystallogr D Struct Biol, 72, 2016
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5I9E
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6BB3
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6ORB
| Full-length S. pombe Mdn1 in the presence of ATP and Rbin-1 | 分子名称: | Midasin | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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6OR5
| Full-length S. pombe Mdn1 in the presence of AMPPNP (ring region) | 分子名称: | Midasin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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5JXT
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5JXR
| Crystal structure of MtISWI | 分子名称: | CHLORIDE ION, Chromatin-remodeling complex ATPase-like protein | 著者 | Chen, Z, Yan, L. | 登録日 | 2016-05-13 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | 主引用文献 | Structure and regulation of the chromatin remodeller ISWI Nature, 540, 2016
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6OR6
| Full-length S. pombe Mdn1 in the presence of AMPPNP (tail region) | 分子名称: | Midasin | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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5TJ8
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3NXP
| Crystal structure of human prethrombin-1 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Chen, Z, Bush-Pelc, L.A, Di Cera, E. | 登録日 | 2010-07-14 | 公開日 | 2010-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of prethrombin-1. Proc.Natl.Acad.Sci.USA, 107, 2010
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5TJ7
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5TJQ
| Structure of WWP2 2,3-linker-HECT | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2 | 著者 | Chen, Z, Gabelli, S.B. | 登録日 | 2016-10-04 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | A Tunable Brake for HECT Ubiquitin Ligases. Mol. Cell, 66, 2017
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3N9H
| Crystal Structural of mutant Y305A in the copper amine oxidase from hansenula polymorpha | 分子名称: | COPPER (II) ION, Peroxisomal primary amine oxidase | 著者 | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | 登録日 | 2010-05-30 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity. Biochemistry, 49, 2010
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3NBB
| Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha | 分子名称: | COPPER (II) ION, Peroxisomal primary amine oxidase | 著者 | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | 登録日 | 2010-06-03 | 公開日 | 2010-08-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity. Biochemistry, 49, 2010
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6JZE
| Crystal structure of VASH2-SVBP complex with the magic triangle I3C | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | 著者 | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | 登録日 | 2019-05-01 | 公開日 | 2019-08-07 | 最終更新日 | 2023-04-05 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer. Nat Commun, 10, 2019
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6JZD
| Crystal structure of peptide-bound VASH2-SVBP complex | 分子名称: | GLU-GLY-GLU-GLU-TYR, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | 著者 | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | 登録日 | 2019-05-01 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.479 Å) | 主引用文献 | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer. Nat Commun, 10, 2019
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6JZC
| Structural basis of tubulin detyrosination | 分子名称: | GLYCEROL, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | 著者 | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | 登録日 | 2019-05-01 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer. Nat Commun, 10, 2019
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5JNC
| Crystal structure for the complex of human carbonic anhydrase IV and 4-aminomethylbenzene sulfonamide | 分子名称: | 4-(aminomethyl)benzene-1-sulfonamide, ACETATE ION, Carbonic anhydrase 4, ... | 著者 | Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. | 登録日 | 2016-04-29 | 公開日 | 2017-05-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
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5JNA
| Crystal structure for the complex of human carbonic anhydrase IV and topiramate | 分子名称: | ACETATE ION, Carbonic anhydrase 4, GLYCEROL, ... | 著者 | Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. | 登録日 | 2016-04-29 | 公開日 | 2017-05-03 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
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3SGZ
| High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole. | 分子名称: | 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 2 | 著者 | Chen, Z, Vignaud, C, Jaafar, A, Gueritte, F, Guenard, D, Lederer, F, Mathews, F.S. | 登録日 | 2011-06-15 | 公開日 | 2012-03-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design. Biochimie, 94, 2012
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5JN8
| Crystal Structure for the complex of human carbonic anhydrase IV and acetazolamide | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ACETATE ION, Carbonic anhydrase 4, ... | 著者 | Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. | 登録日 | 2016-04-29 | 公開日 | 2017-05-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
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