6JQF
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5ZHY
| Structural characterization of the HCoV-229E fusion core | 分子名称: | Spike glycoprotein | 著者 | Zhang, W, Zheng, Q, Yan, M, Chen, X, Yang, H, Zhou, W, Rao, Z. | 登録日 | 2018-03-13 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.441 Å) | 主引用文献 | Structural characterization of the HCoV-229E fusion core. Biochem. Biophys. Res. Commun., 497, 2018
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7YCX
| The structure of INTAC-PEC complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | 登録日 | 2022-07-02 | 公開日 | 2023-03-15 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
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8JDB
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid | 分子名称: | (2R)-2-oxidanyloctanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDD
| Crystal structure of H405A mLDHD in apo form | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDT
| Crystal structure of mLDHD in complex with 2-ketobutanoic acid | 分子名称: | 2-KETOBUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDG
| Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid | 分子名称: | (2R)-2-oxidanylbutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-14 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDU
| Crystal structure of mLDHD in complex with 2-ketovaleric acid | 分子名称: | 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDQ
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid | 分子名称: | (2R)-2-hydroxy-4-methylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDN
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid | 分子名称: | (2R)-2-oxidanylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDX
| Crystal structure of mLDHD in complex with 2-ketoisovaleric acid | 分子名称: | 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDF
| Crystal structure of H405A mLDHD in complex with D-lactate | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDC
| Crystal structure of mLDHD in apo form | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDO
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid | 分子名称: | (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDZ
| Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid | 分子名称: | (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDS
| Crystal structure of mLDHD in complex with Pyruvate | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, PYRUVIC ACID, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.636 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDE
| Crystal structure of mLDHD in complex with D-lactate | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDV
| Crystal structure of mLDHD in complex with 2-ketohexanoic acid | 分子名称: | 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDY
| Crystal structure of mLDHD in complex with 2-ketoisocaproic acid | 分子名称: | 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDP
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid | 分子名称: | DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDR
| Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid | 分子名称: | (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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7VF4
| Crystal structure of Vps75 from Candida albicans | 分子名称: | CHLORIDE ION, SODIUM ION, Vps75 | 著者 | Wang, W, Chen, X, Yang, Z, Chen, X, Li, C, Wang, M. | 登録日 | 2021-09-10 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of histone chaperone Vps75 from Candida albicans. Biochem.Biophys.Res.Commun., 578, 2021
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7CN9
| Cryo-EM structure of SARS-CoV-2 Spike ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ho, M, Chang, Y, Wang, C, Wu, Y, Huang, H, Chen, T, Lo, J.M, Chen, X, Ma, C. | 登録日 | 2020-07-30 | 公開日 | 2020-08-26 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2. Cell Rep, 32, 2020
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7WF5
| c-Src in complex with ponatinib | 分子名称: | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase Src | 著者 | Guo, M, Duan, Y, Dai, S, Chen, X, Chen, Y. | 登録日 | 2021-12-26 | 公開日 | 2022-03-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Structural study of ponatinib in inhibiting SRC kinase. Biochem.Biophys.Res.Commun., 598, 2022
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7WLT
| the Curved Structure of mPIEZO1 in Lipid Bilayer | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... | 著者 | Yang, X, Lin, C, Chen, X, Li, S, Li, X, Xiao, B. | 登録日 | 2022-01-13 | 公開日 | 2022-04-13 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structure deformation and curvature sensing of PIEZO1 in lipid membranes. Nature, 604, 2022
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