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PDB: 444 件

6KZQ
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structure of PTP-MEG2 and NSF-pY83 peptide complex
分子名称: NSF-pY83 peptide, Tyrosine-protein phosphatase non-receptor type 9
著者Xu, Y.F, Chen, X, Yu, X, Sun, J.P.
登録日2019-09-25
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates.
Embo Rep., 22, 2021
5KOC
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Pavine N-methyltransferase in complex with S-adenosylmethionine pH 7
分子名称: Pavine N-methyltransferase, S-ADENOSYLMETHIONINE
著者Torres, M.A, Hoffarth, E, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S.
登録日2016-06-30
公開日2016-09-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
5KOK
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Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25
分子名称: (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, Pavine N-methyltransferase, ...
著者Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S.
登録日2016-06-30
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
358D
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BU of 358d by Molmil
CRYSTAL STRUCTURE OF THE 2:1 NETROPSIN-DNA DECAMER D(CBRCCCCIIIII) COMPLEX WITH END-TO-END BINDING
分子名称: DNA (5'-D(*CP*(CBR)P*CP*CP*CP*IP*IP*IP*IP*I)-3'), NETROPSIN
著者Mitra, S.N, Chen, X, Sundaralingam, M.
登録日1997-10-20
公開日2000-05-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A novel end-to-end binding of two netropsins to the DNA decamers d(CCCCCIIIII)2, d(CCCBr5CCIIIII)2and d(CBr5CCCCIIIII)2.
Nucleic Acids Res., 26, 1998
5KPC
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Pavine N-methyltransferase H206A mutant in complex with S-adenosylmethionine pH 6
分子名称: Pavine N-methyltransferase, S-ADENOSYLMETHIONINE
著者Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S.
登録日2016-07-03
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
5KN4
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Pavine N-methyltransferase apoenzyme pH 6.0
分子名称: Pavine N-methyltransferase
著者Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S.
登録日2016-06-27
公開日2016-09-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
5KPG
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Pavine N-methyltransferase in complex with S-adenosylhomocysteine pH 7
分子名称: Pavine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S.
登録日2016-07-04
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
7SGL
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DNA-PK complex of DNA end processing
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ...
著者Liu, L, Li, J, Chen, X, Yang, W, Gellert, M.
登録日2021-10-06
公開日2022-01-12
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
3G5C
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Structural and biochemical studies on the ectodomain of human ADAM22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION
著者Liu, H, Shim, A, Chen, X, He, X.
登録日2009-02-04
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
1IK1
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BU of 1ik1 by Molmil
Solution Structure of an RNA Hairpin from HRV-14
分子名称: 5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3'
著者Huang, H, Alexandrov, A, Chen, X, Barnes III, T.W, Zhang, H, Dutta, K, Pascal, S.M.
登録日2001-05-01
公開日2001-07-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an RNA hairpin from HRV-14.
Biochemistry, 40, 2001
1MI8
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2.0 Angstrom crystal structure of a DnaB intein from Synechocystis sp. PCC 6803
分子名称: DnaB intein
著者Ding, Y, Chen, X, Ferrandon, S, Xu, M, Rao, Z.
登録日2002-08-22
公開日2003-08-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing
J.Biol.Chem., 278, 2003
6L6H
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Crystal structure of Lpg0189
分子名称: ACETATE ION, GLYCEROL, Uncharacterized protein Lpg0189
著者Ge, H, Chen, X.
登録日2019-10-29
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
6L6G
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Crystal structure of SeMet_Lpg0189
分子名称: GLYCEROL, Uncharacterized protein Lpg0189
著者Ge, H, Chen, X.
登録日2019-10-29
公開日2019-11-27
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
1QET
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TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*AP*UP*GP*UP*CP*C)-3')
著者Mcdowell, J.A, He, L, Chen, X, Turner, D.H.
登録日1997-03-04
公開日1997-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2.
Biochemistry, 36, 1997
1QES
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BU of 1qes by Molmil
TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*AP*GP*UP*UP*CP*C)-3')
著者Mcdowell, J.A, He, L, Chen, X, Turner, D.H.
登録日1997-03-04
公開日1997-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2.
Biochemistry, 36, 1997
1R1V
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BU of 1r1v by Molmil
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the Zn2-form
分子名称: ZINC ION, repressor protein
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R22
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BU of 1r22 by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB (C14S/C61S/C121S mutant) in the Zn2alpha5-form
分子名称: Transcriptional repressor smtB, ZINC ION
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R1U
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BU of 1r1u by Molmil
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the apo-form
分子名称: repressor protein
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R23
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Crystal structure of the cyanobacterial metallothionein repressor SmtB in the Zn1-form (one Zn(II) per dimer)
分子名称: Transcriptional repressor smtB, ZINC ION
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
5ESW
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Crystal structure of Apo hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila
分子名称: PHOSPHATE ION, Purine/pyrimidine phosphoribosyltransferase
著者Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H.
登録日2015-11-17
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
5ESX
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Crystal structure of hypoxanthine-guanine phosphoribosyltransferase complexed with GMP from Legionella pneumophila
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Purine/pyrimidine phosphoribosyltransferase
著者Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H.
登録日2015-11-17
公開日2016-03-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis
J.Struct.Biol., 194, 2016
5X07
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BU of 5x07 by Molmil
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
分子名称: DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta
著者Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y.
登録日2017-01-20
公開日2017-08-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site
Biochemistry, 56, 2017
2HDC
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BU of 2hdc by Molmil
STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX
分子名称: DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3'), PROTEIN (TRANSCRIPTION FACTOR)
著者Jin, C, Marsden, I, Chen, X, Liao, X.
登録日1999-05-05
公開日1999-07-05
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex.
J.Mol.Biol., 289, 1999
1R1T
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BU of 1r1t by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form
分子名称: Transcriptional repressor smtB
著者Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
登録日2003-09-25
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1S8K
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Solution Structure of BmKK4, A Novel Potassium Channel Blocker from Scorpion Buthus martensii Karsch, 25 structures
分子名称: Toxin BmKK4
著者Zhang, N, Chen, X, Li, M, Cao, C, Wang, Y, Hu, G, Wu, H.
登録日2004-02-02
公開日2005-02-08
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of BmKK4, the first member of subfamily alpha-KTx 17 of scorpion toxins
Biochemistry, 43, 2004

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