7SXM
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6CIO
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4LZO
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![BU of 4lzo by Molmil](/molmil-images/mine/4lzo) | Crystal structure of human PRS1 A87T mutant | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | 著者 | Chen, P, Teng, M, Li, X. | 登録日 | 2013-07-31 | 公開日 | 2015-02-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4LYG
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![BU of 4lyg by Molmil](/molmil-images/mine/4lyg) | Crystal structure of human PRS1 E43T mutant | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | 著者 | Chen, P, Teng, M, Li, X. | 登録日 | 2013-07-31 | 公開日 | 2015-02-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4LZN
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![BU of 4lzn by Molmil](/molmil-images/mine/4lzn) | Crystal structure of human PRS1 D65N mutant | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | 著者 | Chen, P, Teng, M, Li, X. | 登録日 | 2013-07-31 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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4M0P
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![BU of 4m0p by Molmil](/molmil-images/mine/4m0p) | Crystal structure of human PRS1 M115T mutant | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | 著者 | Chen, P, Teng, M, Li, X. | 登録日 | 2013-08-01 | 公開日 | 2015-02-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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8X7N
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9BPF
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9BOO
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![BU of 9boo by Molmil](/molmil-images/mine/9boo) | Crystal structure of MERS-CoV Nsp5 in complex with PF-07817883 | 分子名称: | 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide | 著者 | Chen, P, Arutyunova, E, Lemieux, M.J. | 登録日 | 2024-05-05 | 公開日 | 2024-08-07 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (M pro ) of SARS-CoV-2 and MERS-CoV. Jacs Au, 4, 2024
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1IA8
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![BU of 1ia8 by Molmil](/molmil-images/mine/1ia8) | THE 1.7 A CRYSTAL STRUCTURE OF HUMAN CELL CYCLE CHECKPOINT KINASE CHK1 | 分子名称: | CHK1 CHECKPOINT KINASE, SULFATE ION | 著者 | Chen, P, Luo, C, Deng, Y, Ryan, K, Register, J, Margosiak, S, Tempczyk-Russell, A, Nguyen, B, Myers, P, Lundgren, K, Chen Kan, C.-C, O'Connor, P.M. | 登録日 | 2001-03-22 | 公開日 | 2001-04-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation. Cell(Cambridge,Mass.), 100, 2000
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6OQ5
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![BU of 6oq5 by Molmil](/molmil-images/mine/6oq5) | Structure of the full-length Clostridium difficile toxin B in complex with 3 VHHs | 分子名称: | 5D, 7F, E3, ... | 著者 | Chen, P, Lam, K, Jin, R. | 登録日 | 2019-04-25 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.87 Å) | 主引用文献 | Structure of the full-length Clostridium difficile toxin B. Nat.Struct.Mol.Biol., 26, 2019
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6OQ6
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6OQ8
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6OQ7
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![BU of 6oq7 by Molmil](/molmil-images/mine/6oq7) | Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH E3 | 分子名称: | E3, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Chen, P, Lam, K, Jin, R. | 登録日 | 2019-04-25 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure of the full-length Clostridium difficile toxin B. Nat.Struct.Mol.Biol., 26, 2019
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6OUW
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6OUV
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7S2X
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![BU of 7s2x by Molmil](/molmil-images/mine/7s2x) | Structure of SalC, a gamma-lactam-beta-lactone bicyclase for salinosporamide biosynthesis | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, POTASSIUM ION, SalC | 著者 | Chen, P.Y.-T, Trivella, D.B.B, Bauman, K.D, Moore, B.S. | 登録日 | 2021-09-04 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Enzymatic assembly of the salinosporamide gamma-lactam-beta-lactone anticancer warhead. Nat.Chem.Biol., 18, 2022
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7S5L
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1PI2
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2BV6
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![BU of 2bv6 by Molmil](/molmil-images/mine/2bv6) | Crystal structure of MgrA, a global regulator and major virulence determinant in Staphylococcus aureus | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR MGRA, SULFATE ION | 著者 | Chen, P.R, Bae, T, Williams, W.A, Duguid, E.M, Rice, P.A, Schneewind, O, He, C. | 登録日 | 2005-06-22 | 公開日 | 2006-09-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An Oxidation-Sensing Mechanism is Used by the Global Regulator Mgra in Staphylococcus Aureus. Nat.Chem.Biol., 2, 2006
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1GRC
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5CNV
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![BU of 5cnv by Molmil](/molmil-images/mine/5cnv) | Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to GDP and TTP at 3.20 Angstroms resolution | 分子名称: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. | 登録日 | 2015-07-18 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
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7ML7
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5CNS
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![BU of 5cns by Molmil](/molmil-images/mine/5cns) | Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to CDP and dATP at 2.97 Angstroms resolution | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, ... | 著者 | Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. | 登録日 | 2015-07-18 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.975 Å) | 主引用文献 | Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
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5CNT
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![BU of 5cnt by Molmil](/molmil-images/mine/5cnt) | Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ... | 著者 | Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. | 登録日 | 2015-07-18 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
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