1IA8

THE 1.7 A CRYSTAL STRUCTURE OF HUMAN CELL CYCLE CHECKPOINT KINASE CHK1

Summary for 1IA8

DescriptorCHK1 CHECKPOINT KINASE, SULFATE ION (3 entities in total)
Functional Keywordsprotein kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus O14757
Total number of polymer chains1
Total molecular weight33139.05
Authors
Chen, P.,Luo, C.,Deng, Y.,Ryan, K.,Register, J.,Margosiak, S.,Tempczyk-Russell, A.,Nguyen, B.,Myers, P.,Lundgren, K.,Chen Kan, C.-C.,O'Connor, P.M. (deposition date: 2001-03-22, release date: 2001-04-18, Last modification date: 2018-01-31)
Primary citation
Chen, P.,Luo, C.,Deng, Y.,Ryan, K.,Register, J.,Margosiak, S.,Tempczyk-Russell, A.,Nguyen, B.,Myers, P.,Lundgren, K.,Kan, C.C.,O'Connor, P.M.
The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation.
Cell(Cambridge,Mass.), 100:681-692, 2000
PubMed: 10761933 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(00)80704-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers191.1%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution