2P17
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![BU of 2p17 by Molmil](/molmil-images/mine/2p17) | Crystal structure of GK1651 from Geobacillus kaustophilus | 分子名称: | FE (III) ION, Pirin-like protein | 著者 | Zhu, J, Swindell II, J.T, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-02 | 公開日 | 2007-05-01 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Crystal structure of GK1651 from Geobacillus kaustophilus To be Published
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2P62
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![BU of 2p62 by Molmil](/molmil-images/mine/2p62) | Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3 | 分子名称: | Hypothetical protein PH0156 | 著者 | Fu, Z.-Q, Chen, L, Zhu, J, Swindell, J.T, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-16 | 公開日 | 2007-04-17 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3 To be Published
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3SQ6
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![BU of 3sq6 by Molmil](/molmil-images/mine/3sq6) | Crystal Structures of the Ligand Binding Domain of a Pentameric Alpha7 Nicotinic Receptor Chimera with its Agonist Epibatidine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIBATIDINE, ... | 著者 | Li, S.-X, Huang, S, Bren, N, Noridomi, K, Dellisanti, C, Sine, S, Chen, L. | 登録日 | 2011-07-05 | 公開日 | 2011-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Ligand-binding domain of an alpha 7-nicotinic receptor chimera and its complex with agonist. Nat.Neurosci., 14, 2011
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2PHC
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![BU of 2phc by Molmil](/molmil-images/mine/2phc) | Crystal structure of conserved uncharacterized protein PH0987 from Pyrococcus horikoshii | 分子名称: | Uncharacterized protein PH0987 | 著者 | Swindell II, J.T, Chen, L, Zhu, J, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-10 | 公開日 | 2007-05-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structure of conserved uncharacterized protein PH0987 from Pyrococcus horikoshii. To be Published
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2PH7
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![BU of 2ph7 by Molmil](/molmil-images/mine/2ph7) | Crystal structure of AF2093 from Archaeoglobus fulgidus | 分子名称: | Uncharacterized protein AF_2093 | 著者 | Chang, J.C, Yang, H, Hwang, J, Zhu, J, Chen, L, Fu, Z.-Q, Xu, H, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2007-04-10 | 公開日 | 2007-05-08 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of AF2093 from Archaeoglobus fulgidus. To be Published
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2PW6
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![BU of 2pw6 by Molmil](/molmil-images/mine/2pw6) | Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12 | 分子名称: | Uncharacterized protein ygiD, ZINC ION | 著者 | Newton, M.G, Takagi, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokayama, S, Li, Y, Chen, L, Zhu, J, Ruble, J, Liu, Z.J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-10 | 公開日 | 2007-06-12 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12. To be Published
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7FIM
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![BU of 7fim by Molmil](/molmil-images/mine/7fim) | Cryo-EM structure of the tirzepatide (LY3298176)-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,human glucagon like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-07-31 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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3PZ8
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2QC1
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![BU of 2qc1 by Molmil](/molmil-images/mine/2qc1) | Crystal structure of the extracellular domain of the nicotinic acetylcholine receptor 1 subunit bound to alpha-bungarotoxin at 1.9 A resolution | 分子名称: | Acetylcholine receptor subunit alpha, Alpha-bungarotoxin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Dellisanti, C.D, Yao, Y, Stroud, J.C, Wang, Z, Chen, L. | 登録日 | 2007-06-18 | 公開日 | 2007-08-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution. Nat.Neurosci., 10, 2007
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2NN2
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6C9L
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![BU of 6c9l by Molmil](/molmil-images/mine/6c9l) | MEF2B Apo Protein Structure | 分子名称: | Myocyte-specific enhancer factor 2B | 著者 | Lei, X, Chen, L. | 登録日 | 2018-01-26 | 公開日 | 2018-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Apo MEF2B Reveals New Insights in DNA Binding and Cofactor Interaction. Biochemistry, 57, 2018
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3SQ9
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![BU of 3sq9 by Molmil](/molmil-images/mine/3sq9) | Crystal Structures of the Ligand Binding Domain of a Pentameric Alpha7 Nicotinic Receptor Chimera | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuronal acetylcholine receptor subunit alpha-7, ... | 著者 | Li, S.-X, Huang, S, Bren, N, Noridomi, K, Dellisanti, C, Sine, S, Chen, L. | 登録日 | 2011-07-05 | 公開日 | 2011-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Ligand-binding domain of an alpha 7-nicotinic receptor chimera and its complex with agonist. Nat.Neurosci., 14, 2011
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4JA8
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![BU of 4ja8 by Molmil](/molmil-images/mine/4ja8) | Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor | 分子名称: | 1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-yl-phenyl]-3-[3-(trifluoromethyl)phenyl]urea, CALCIUM ION, GLYCEROL, ... | 著者 | Wei, W, Chen, L, Wu, M, Jiang, F, Travins, J, Qian, K, DeLaBarre, B. | 登録日 | 2013-02-18 | 公開日 | 2013-04-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science, 340, 2013
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3M4T
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![BU of 3m4t by Molmil](/molmil-images/mine/3m4t) | |
3R6J
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![BU of 3r6j by Molmil](/molmil-images/mine/3r6j) | Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999 | 分子名称: | 1,2-ETHANEDIOL, VP1 protein | 著者 | Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D. | 登録日 | 2011-03-21 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability. J.Virol., 85, 2011
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3O3K
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![BU of 3o3k by Molmil](/molmil-images/mine/3o3k) | Crystal structure of AF1382 from Archaeoglobus fulgidus | 分子名称: | Uncharacterized protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-07-24 | 公開日 | 2010-08-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
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3MU6
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![BU of 3mu6 by Molmil](/molmil-images/mine/3mu6) | Inhibiting the Binding of Class IIa Histone Deacetylases to Myocyte Enhancer Factor-2 by Small Molecules | 分子名称: | (3E)-N~8~-(2-aminophenyl)-N~1~-phenyloct-3-enediamide, DNA (5'-D(*AP*AP*AP*GP*CP*TP*AP*TP*TP*AP*TP*TP*AP*GP*CP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*GP*CP*TP*AP*AP*TP*AP*AP*TP*AP*GP*CP*TP*T)-3'), ... | 著者 | Jayathilaka, N, Han, A, Gaffney, K, Dey, R, He, J, Ye, J, Gao, T, Petasis, N.A, Chen, L. | 登録日 | 2010-05-01 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.434 Å) | 主引用文献 | Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2. Nucleic Acids Res., 40, 2012
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3OV8
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![BU of 3ov8 by Molmil](/molmil-images/mine/3ov8) | Crystal structure of AF1382 from Archaeoglobus fulgidus, High resolution | 分子名称: | ACETATE ION, CHLORIDE ION, Protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Hao, X, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-09-16 | 公開日 | 2011-11-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8501 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
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3P8F
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3P8G
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![BU of 3p8g by Molmil](/molmil-images/mine/3p8g) | Crystal Structure of MT-SP1 in complex with benzamidine | 分子名称: | 1,2-ETHANEDIOL, BENZAMIDINE, GLUTATHIONE, ... | 著者 | Yuan, C, Huang, M, Chen, L. | 登録日 | 2010-10-13 | 公開日 | 2011-08-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. Bmc Struct.Biol., 11, 2011
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3PZ7
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8IKL
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![BU of 8ikl by Molmil](/molmil-images/mine/8ikl) | Cryo-EM structure of the CD97-G13 complex | 分子名称: | Adhesion G protein-coupled receptor E5, Guanine nucleotide-binding protein G(13) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P. | 登録日 | 2023-02-28 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | 主引用文献 | Conformational transitions and activation of the adhesion receptor CD97. Mol.Cell, 84, 2024
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8IKJ
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![BU of 8ikj by Molmil](/molmil-images/mine/8ikj) | Cryo-EM structure of the inactive CD97 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor E5,Soluble cytochrome b562,Adhesion G protein-coupled receptor E5 subunit beta | 著者 | Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P, Guo, J, Qin, J, Shen, D, Ji, S, Zang, S, Zhang, H, Wang, W, Shen, Q, Sun, P, Zhang, Y. | 登録日 | 2023-02-28 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Conformational transitions and activation of the adhesion receptor CD97. Mol.Cell, 84, 2024
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8SV7
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7XOW
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![BU of 7xow by Molmil](/molmil-images/mine/7xow) | Structural insights into human brain gut peptide cholecystokinin receptors | 分子名称: | Gastrin, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. | 登録日 | 2022-05-01 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into human brain-gut peptide cholecystokinin receptors. Cell Discov, 8, 2022
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