8I3G
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![BU of 8i3g by Molmil](/molmil-images/mine/8i3g) | Crystal structure of Eaf3-Eaf7 complex | 分子名称: | Chromatin modification-related protein EAF3, Chromatin modification-related protein EAF7 | 著者 | Chen, Z, Xu, C. | 登録日 | 2023-01-17 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4. Cell Discov, 9, 2023
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8I3F
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7U1B
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6TTK
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![BU of 6ttk by Molmil](/molmil-images/mine/6ttk) | Crystal structure of the kelch domain of human KLHL12 in complex with DVL1 peptide | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DVL1, ... | 著者 | Chen, Z, Williams, E, Pike, A.C.W, Strain-Damerell, C, Wang, D, Chalk, R, Burgess-Brown, N, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2019-12-27 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.383 Å) | 主引用文献 | Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12. Open Biology, 10, 2020
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8TO0
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![BU of 8to0 by Molmil](/molmil-images/mine/8to0) | 48-nm repeating structure of doublets from mouse sperm flagella | 分子名称: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | 著者 | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | 登録日 | 2023-08-02 | 公開日 | 2023-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell, 186, 2023
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8EOI
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![BU of 8eoi by Molmil](/molmil-images/mine/8eoi) | Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. | 登録日 | 2022-10-03 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | EMC chaperone-Ca V structure reveals an ion channel assembly intermediate. Nature, 619, 2023
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8EOG
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![BU of 8eog by Molmil](/molmil-images/mine/8eog) | Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine | 分子名称: | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. | 登録日 | 2022-10-03 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | EMC chaperone-Ca V structure reveals an ion channel assembly intermediate. Nature, 619, 2023
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8FD7
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![BU of 8fd7 by Molmil](/molmil-images/mine/8fd7) | Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin | 分子名称: | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Z, Mondal, A, Minor, D.L. | 登録日 | 2022-12-02 | 公開日 | 2023-03-22 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for Ca V alpha 2 delta :gabapentin binding. Nat.Struct.Mol.Biol., 30, 2023
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8D6T
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![BU of 8d6t by Molmil](/molmil-images/mine/8d6t) | Rana catesbeiana saxiphilin mutant - Y558I:STX (co-crystal) | 分子名称: | CACODYLATE ION, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | 著者 | Chen, Z, Zakrzewska, S, Minor, D.L. | 登録日 | 2022-06-06 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6P
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8D6Q
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8D6S
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![BU of 8d6s by Molmil](/molmil-images/mine/8d6s) | Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal) | 分子名称: | Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | 著者 | Chen, Z, Zakrzewska, S, Minor, D.L. | 登録日 | 2022-06-06 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6U
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![BU of 8d6u by Molmil](/molmil-images/mine/8d6u) | Rana catesbeiana saxiphilin:F-STX (soaked) | 分子名称: | (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, Saxiphilin | 著者 | Chen, Z, Zakrzewska, S, Minor, D.L. | 登録日 | 2022-06-06 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8JT8
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![BU of 8jt8 by Molmil](/molmil-images/mine/8jt8) | Crystal structure of 5-HT2AR in complex with (R)-IHCH-7179 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one, 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, ... | 著者 | Chen, Z, Fan, L, Wang, S. | 登録日 | 2023-06-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Flexible scaffold-based cheminformatics approach for polypharmacological drug design. Cell, 187, 2024
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6V09
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![BU of 6v09 by Molmil](/molmil-images/mine/6v09) | Crystal structure of human recombinant Beta-2 glycoprotein I short tag (ST-B2GPI) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, SULFATE ION, ... | 著者 | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | 登録日 | 2019-11-18 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome. J.Biol.Chem., 295, 2020
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8JT6
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![BU of 8jt6 by Molmil](/molmil-images/mine/8jt6) | 5-HT1A-Gi in complex with compound (R)-IHCH-7179 | 分子名称: | 1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Chen, Z, Xu, P, Huang, S, Xu, H.E, Wang, S. | 登録日 | 2023-06-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Flexible scaffold-based cheminformatics approach for polypharmacological drug design. Cell, 187, 2024
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5NKP
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![BU of 5nkp by Molmil](/molmil-images/mine/5nkp) | Crystal structure of the human KLHL3 Kelch domain in complex with a WNK3 peptide | 分子名称: | CHLORIDE ION, CITRIC ACID, Kelch-like protein 3, ... | 著者 | Chen, Z, Sorrell, F.J, Pinkas, D.M, Williams, E, Mathea, S, Goubin, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Burgess-Brown, N, Bountra, C, Bullock, A. | 登録日 | 2017-03-31 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the human KLHL3 Kelch domain in complex with a WNK3 peptide To Be Published
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6GY5
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![BU of 6gy5 by Molmil](/molmil-images/mine/6gy5) | Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Death-associated protein kinase 1, ... | 著者 | Chen, Z, Hozjan, V, Strain-Damerell, C, Williams, E, Wang, D, Cooper, C.D.O, Sanvitale, C.E, Fairhead, M, Carpenter, E.P, Pike, A.C.W, Krojer, T, Srikannathasan, V, Sorrell, F, Johansson, C, Mathea, S, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2018-06-28 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.086 Å) | 主引用文献 | Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase. Structure, 27, 2019
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6OR6
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![BU of 6or6 by Molmil](/molmil-images/mine/6or6) | Full-length S. pombe Mdn1 in the presence of AMPPNP (tail region) | 分子名称: | Midasin | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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8SYN
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![BU of 8syn by Molmil](/molmil-images/mine/8syn) | Human VPS35L/VPS29/VPS26C Complex | 分子名称: | VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 26C, Vacuolar protein sorting-associated protein 29 | 著者 | Chen, Z, Chen, B, Burstein, E, Han, Y. | 登録日 | 2023-05-25 | 公開日 | 2023-11-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural organization of the retriever-CCC endosomal recycling complex. Nat.Struct.Mol.Biol., 31, 2024
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8SYM
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![BU of 8sym by Molmil](/molmil-images/mine/8sym) | Human VPS29/VPS35L Complex (Locally refined map) | 分子名称: | VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 29 | 著者 | Chen, Z, Chen, B, Burstein, E, Han, Y. | 登録日 | 2023-05-25 | 公開日 | 2023-11-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural organization of the retriever-CCC endosomal recycling complex. Nat.Struct.Mol.Biol., 31, 2024
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8SYO
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![BU of 8syo by Molmil](/molmil-images/mine/8syo) | Human Retriever VPS35L/VPS29/VPS26C Complex (Composite Map) | 分子名称: | VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 26C, Vacuolar protein sorting-associated protein 29 | 著者 | Chen, Z, Chen, B, Burstein, E, Han, Y. | 登録日 | 2023-05-25 | 公開日 | 2023-11-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural organization of the retriever-CCC endosomal recycling complex. Nat.Struct.Mol.Biol., 31, 2024
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6V06
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![BU of 6v06 by Molmil](/molmil-images/mine/6v06) | Crystal structure of Beta-2 glycoprotein I purified from plasma (pB2GPI) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-glycoprotein 1, ... | 著者 | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | 登録日 | 2019-11-18 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome. J.Biol.Chem., 295, 2020
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6OR5
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![BU of 6or5 by Molmil](/molmil-images/mine/6or5) | Full-length S. pombe Mdn1 in the presence of AMPPNP (ring region) | 分子名称: | Midasin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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6ORB
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![BU of 6orb by Molmil](/molmil-images/mine/6orb) | Full-length S. pombe Mdn1 in the presence of ATP and Rbin-1 | 分子名称: | Midasin | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
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