2HP6
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![BU of 2hp6 by Molmil](/molmil-images/mine/2hp6) | Crystal structure of the OXA-10 W154A mutant at pH 7.5 | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | Deposit date: | 2006-07-17 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2HP9
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![BU of 2hp9 by Molmil](/molmil-images/mine/2hp9) | Crystal Structure of the OXA-10 W154A mutant at pH 6.0 | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | Deposit date: | 2006-07-17 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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1K6S
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![BU of 1k6s by Molmil](/molmil-images/mine/1k6s) | STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH A PHENYLBORONIC ACID | Descriptor: | 4-IODO-ACETAMIDO PHENYLBORONIC ACID, Beta-lactamase PSE-2, CALCIUM ION, ... | Authors: | Kerff, F, Fonze, E, Sauvage, E, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-17 | Release date: | 2003-06-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | CRYSTAL STRUCTURE OF CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH DIFFERENT SUBSTRATES AND ONE INHIBITOR. To be Published
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1K6R
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![BU of 1k6r by Molmil](/molmil-images/mine/1k6r) | STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH MOXALACTAM | Descriptor: | (2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBO XYLIC ACID, Beta-lactamase PSE-2 | Authors: | Kerff, F, Fonze, E, Sauvage, E, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-17 | Release date: | 2003-06-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | CRYSTAL STRUCTURE OF CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH DIFFERENT SUBSTRATES AND ONE INHIBITOR. To be Published
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1K4E
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![BU of 1k4e by Molmil](/molmil-images/mine/1k4e) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASES OXA-10 DETERMINED BY MAD PHASING WITH SELENOMETHIONINE | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Fonze, E, Bouillene, F, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-08 | Release date: | 2001-10-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | STRUCTURE OF CLASS D BETA-LACTAMASE OXA-2 To be Published
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1NRF
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![BU of 1nrf by Molmil](/molmil-images/mine/1nrf) | C-terminal domain of the Bacillus licheniformis BlaR penicillin-receptor | Descriptor: | REGULATORY PROTEIN BLAR1 | Authors: | Kerff, F, Charlier, P, Columbo, M.L, Sauvage, E, Brans, A, Frere, J.M, Joris, B, Fonze, E. | Deposit date: | 2003-01-24 | Release date: | 2004-01-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the sensor domain of the BlaR penicillin receptor from Bacillus licheniformis. Biochemistry, 42, 2003
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5LWF
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![BU of 5lwf by Molmil](/molmil-images/mine/5lwf) | Structure of a single domain camelid antibody fragment cAb-G10S in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | ACETATE ION, Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-G10S | Authors: | Vettore, N, Kerff, F, Pain, C, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2016-09-16 | Release date: | 2017-11-15 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To Be Published
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1K4F
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![BU of 1k4f by Molmil](/molmil-images/mine/1k4f) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Fonze, E, Bouillene, F, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-08 | Release date: | 2001-10-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the class D beta-lactamase OXA-2 To be Published
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3D30
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![BU of 3d30 by Molmil](/molmil-images/mine/3d30) | Structure of an expansin like protein from Bacillus Subtilis at 1.9A resolution | Descriptor: | Expansin like protein, FORMIC ACID, GLYCEROL | Authors: | Kerff, F, Petrella, S, Herman, R, Sauvage, E, Joris, B, Charlier, P. | Deposit date: | 2008-05-09 | Release date: | 2008-10-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization. Proc.Natl.Acad.Sci.USA, 105, 2008
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3D2Z
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![BU of 3d2z by Molmil](/molmil-images/mine/3d2z) | Complex of the N-acetylmuramyl-L-alanine amidase AmiD from E.coli with the product L-Ala-D-gamma-Glu-L-Lys | Descriptor: | CHLORIDE ION, L-Ala-D-gamma-Glu-L-Lys peptide, N-acetylmuramoyl-L-alanine amidase amiD, ... | Authors: | Kerff, F, Petrella, S, Herman, R, Sauvage, E, Mercier, F, Luxen, A, Frere, J.M, Joris, B, Charlier, P. | Deposit date: | 2008-05-09 | Release date: | 2009-06-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Specific Structural Features of the N-Acetylmuramoyl-l-Alanine Amidase AmiD from Escherichia coli and Mechanistic Implications for Enzymes of This Family. J.Mol.Biol., 397, 2010
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3B3X
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![BU of 3b3x by Molmil](/molmil-images/mine/3b3x) | Crystal structure of class A beta-lactamase of Bacillus licheniformis BS3 with aminocitrate | Descriptor: | 2-(carboxymethyl)-D-aspartic acid, Beta-lactamase | Authors: | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2007-10-23 | Release date: | 2007-11-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis Bioorg.Med.Chem.Lett., 18, 2008
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3D2Y
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![BU of 3d2y by Molmil](/molmil-images/mine/3d2y) | Complex of the N-acetylmuramyl-L-alanine amidase AmiD from E.coli with the substrate anhydro-N-acetylmuramic acid-L-Ala-D-gamma-Glu-L-Lys | Descriptor: | Anhydro-N-acetylmuramic acid-L-Ala-D-gamma-Glu-L-Lys, GLYCEROL, N-acetylmuramoyl-L-alanine amidase amiD | Authors: | Kerff, F, Petrella, S, Herman, R, Sauvage, E, Mercier, F, Luxen, A, Frere, J.M, Joris, B, Charlier, P. | Deposit date: | 2008-05-09 | Release date: | 2009-06-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Specific Structural Features of the N-Acetylmuramoyl-l-Alanine Amidase AmiD from Escherichia coli and Mechanistic Implications for Enzymes of This Family. J.Mol.Biol., 397, 2010
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2Y91
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![BU of 2y91 by Molmil](/molmil-images/mine/2y91) | Crystal structure of class A beta-lactamase from Bacillus licheniformis BS3 with clavulanic acid | Descriptor: | 5-HYDROXY-3-OXOPENTANOIC ACID, BETA-LACTAMASE, CITRIC ACID, ... | Authors: | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2011-02-11 | Release date: | 2012-02-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Novel Fragments of Clavulanate Observed in the Structure of the Class a Beta-Lactamase from Bacillus Licheniformis Bs3. J.Antimicrob.Chemother., 67, 2012
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1ESU
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![BU of 1esu by Molmil](/molmil-images/mine/1esu) | S235A MUTANT OF TEM1 BETA-LACTAMASE | Descriptor: | BETA-LACTAMASE, SULFATE ION | Authors: | Fonze, E, Charlier, P. | Deposit date: | 2000-04-11 | Release date: | 2000-05-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant. Acta Crystallogr.,Sect.D, 51, 1995
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2WKE
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![BU of 2wke by Molmil](/molmil-images/mine/2wke) | Crystal structure of the Actinomadura R39 DD-peptidase inhibited by 6- beta-iodopenicillanate. | Descriptor: | (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ... | Authors: | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2009-06-10 | Release date: | 2009-12-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131, 2009
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2WGW
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![BU of 2wgw by Molmil](/molmil-images/mine/2wgw) | Crystal structure of the OXA-10 V117T mutant at pH 8.0 | Descriptor: | BETA-LACTAMASE OXA-10, GLYCEROL, SULFATE ION | Authors: | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | Deposit date: | 2009-04-27 | Release date: | 2010-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2X01
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![BU of 2x01 by Molmil](/molmil-images/mine/2x01) | CRYSTAL STRUCTURE OF THE OXA-10 S67A MUTANT AT PH 7 | Descriptor: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, SULFATE ION, ... | Authors: | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Galleni, M, Charlier, P. | Deposit date: | 2009-12-04 | Release date: | 2010-12-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evidence of Chloride Inhibition and Impact of the Hydrophobic Core on the Lysine Carboxylated in Class D Beta-Lactamase To be Published
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2WKI
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![BU of 2wki by Molmil](/molmil-images/mine/2wki) | Crystal structure of the OXA-10 K70C mutant at pH 7.0 | Descriptor: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, GLYCEROL, ... | Authors: | Vercheval, L, Bauvois, C, Kerff, F, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | Deposit date: | 2009-06-11 | Release date: | 2010-08-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2XDM
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![BU of 2xdm by Molmil](/molmil-images/mine/2xdm) | Crystal structure of a complex between Actinomadura R39 DD peptidase and a peptidoglycan mimetic boronate inhibitor | Descriptor: | (D-ALPHA-AMINOPIMELYLAMINO)-D-1-ETHYLBORONIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COBALT (II) ION, ... | Authors: | Rocaboy, M, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2010-05-04 | Release date: | 2010-07-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of a Complex between the Actinomadura R39 Dd-Peptidase and a Peptidoglycan- Mimetic Boronate Inhibitor: Interpretation of a Transition State Analogue in Terms of Catalytic Mechanism. Biochemistry, 49, 2010
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2Y59
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![BU of 2y59 by Molmil](/molmil-images/mine/2y59) | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | Descriptor: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2011-01-12 | Release date: | 2011-07-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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2Y4A
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![BU of 2y4a by Molmil](/molmil-images/mine/2y4a) | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | Descriptor: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2011-01-05 | Release date: | 2011-07-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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2Y55
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![BU of 2y55 by Molmil](/molmil-images/mine/2y55) | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | Descriptor: | ACETONE, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | Authors: | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2011-01-12 | Release date: | 2011-07-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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2XLN
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![BU of 2xln by Molmil](/molmil-images/mine/2xln) | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor | Descriptor: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE,, SULFATE ION, ... | Authors: | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2010-07-21 | Release date: | 2011-01-26 | Last modified: | 2014-06-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors Acs Med.Chem.Lett., 2, 2011
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2XK1
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![BU of 2xk1 by Molmil](/molmil-images/mine/2xk1) | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor | Descriptor: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, ... | Authors: | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2010-07-07 | Release date: | 2011-01-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors Acs Med.Chem.Lett., 2, 2011
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2X02
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![BU of 2x02 by Molmil](/molmil-images/mine/2x02) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.35 A RESOLUTION | Descriptor: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Vercheval, L, Kerff, F, Sauvage, E, Herman, R, Galleni, M, Charlier, P. | Deposit date: | 2009-12-04 | Release date: | 2010-12-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Impact of the Carboxylated Lysine on the Acylation and Deacylation Step in Class D Beta-Lactamase To be Published
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