2Y91

Crystal structure of class A beta-lactamase from Bacillus licheniformis BS3 with clavulanic acid

Summary for 2Y91

• Entry DOI: 10.2210/pdb2y91/pdb
• Related: 2X71
• Descriptor: BETA-LACTAMASE, 5-HYDROXY-3-OXOPENTANOIC ACID, CITRIC ACID, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: BACILLUS LICHENIFORMIS
• Total number of polymer chains: 2
• Total formula weight: 59903.37

Authors

Power, P.,Sauvage, E.,Herman, R.,Kerff, F.,Charlier, P. (deposition date: 2011-02-11, release date: 2012-02-22, Last modification date: 2023-12-20)

Primary citation

Power, P.,Mercuri, P.,Herman, R.,Kerff, F.,Gutkind, G.,Dive, G.,Galleni, M.,Charlier, P.,Sauvage, E.
Novel Fragments of Clavulanate Observed in the Structure of the Class a Beta-Lactamase from Bacillus Licheniformis Bs3.
J.Antimicrob.Chemother., 67:2379-, 2012

PubMed Abstract: Our aim was to unravel the inactivation pathway of the class A β-lactamase produced by Bacillus licheniformis BS3 (BS3) by clavulanate.

PubMed: 22773738
DOI: 10.1093/JAC/DKS231

Experimental method

X-RAY DIFFRACTION (2 Å)