2XLN
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor
Summary for 2XLN
Entry DOI | 10.2210/pdb2xln/pdb |
Related | 1W79 1W8Q 1W8Y 2VGJ 2VGK 2WKE 2XDM 2XK1 2Y4A 2Y55 2Y59 |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE,, [(1S)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}ETHYL]BORONIC ACID, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, peptidoglycan |
Biological source | ACTINOMADURA SP |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 203098.42 |
Authors | Sauvage, E.,Herman, R.,Kerff, F.,Rocaboy, M.,Charlier, P. (deposition date: 2010-07-21, release date: 2011-01-26, Last modification date: 2014-06-18) |
Primary citation | Woon, E.C.Y.,Zervosen, A.,Sauvage, E.,Simmons, K.J.,Ivec, M.,Inglis, S.R.,Fishwick, C.W.G.,Gobec, S.,Charlier, P.,Luxen, A.,Schofield, C.J. Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors Acs Med.Chem.Lett., 2:219-, 2011 Cited by PubMed: 24900305DOI: 10.1021/ML100260X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report