6XGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xgz by Molmil](/molmil-images/mine/6xgz) | Crystal structure of E. coli MlaFB ABC transport subunits in the monomeric state | Descriptor: | 1,2-ETHANEDIOL, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ... | Authors: | Chang, Y, Bhabha, G, Ekiert, D.C. | Deposit date: | 2020-06-18 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Elife, 9, 2020
|
|
6E31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e31 by Molmil](/molmil-images/mine/6e31) | Crystal structure of RIAM in an autoinhibited configuration. | Descriptor: | Rap1-interacting adapter molecule | Authors: | Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J. | Deposit date: | 2018-07-12 | Release date: | 2019-02-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
7YPL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ypl by Molmil](/molmil-images/mine/7ypl) | |
6LSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lsq by Molmil](/molmil-images/mine/6lsq) | |
4W8P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4w8p by Molmil](/molmil-images/mine/4w8p) | Crystal structure of RIAM TBS1 in complex with talin R7R8 domains | Descriptor: | 1,2-ETHANEDIOL, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 | Authors: | Chang, Y.C.E, Zhang, H, Wu, J. | Deposit date: | 2014-08-25 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling. Structure, 22, 2014
|
|
3MO0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mo0 by Molmil](/molmil-images/mine/3mo0) | Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E11 | Descriptor: | 1,2-ETHANEDIOL, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | Authors: | Chang, Y, Horton, J.R, Cheng, X. | Deposit date: | 2010-04-22 | Release date: | 2010-06-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
|
|
4GMV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gmv by Molmil](/molmil-images/mine/4gmv) | |
4GN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gn1 by Molmil](/molmil-images/mine/4gn1) | Crystal Structure of the RA and PH domains of Lamellipodin | Descriptor: | MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1 | Authors: | Chang, Y.C.E, Wu, J. | Deposit date: | 2012-08-16 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4, 2013
|
|
7YSI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ysi by Molmil](/molmil-images/mine/7ysi) | Crystal structure of thioredoxin 2 | Descriptor: | Thiol disulfide reductase thioredoxin, ZINC ION | Authors: | Chang, Y.J, Park, H.H. | Deposit date: | 2022-08-12 | Release date: | 2023-03-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.202 Å) | Cite: | Comparison of the structure and activity of thioredoxin 2 and thioredoxin 1 from Acinetobacter baumannii. Iucrj, 10, 2023
|
|
8XMI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xmi by Molmil](/molmil-images/mine/8xmi) | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA, C1 symmetry | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | Authors: | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | Deposit date: | 2023-12-27 | Release date: | 2024-04-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|
8XMH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xmh by Molmil](/molmil-images/mine/8xmh) | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA, vertical C2 symmetry axis | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | Authors: | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | Deposit date: | 2023-12-27 | Release date: | 2024-04-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|
8K1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k1t by Molmil](/molmil-images/mine/8k1t) | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of MgCl2 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | Authors: | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | Deposit date: | 2023-07-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.48 Å) | Cite: | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|
8K1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k1u by Molmil](/molmil-images/mine/8k1u) | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | Authors: | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | Deposit date: | 2023-07-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|
8K1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k1s by Molmil](/molmil-images/mine/8k1s) | Potassium transporter KtrAB from Bacillus subtilis in ADP-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | Authors: | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | Deposit date: | 2023-07-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB. Nat Commun, 15, 2024
|
|
6XGY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xgy by Molmil](/molmil-images/mine/6xgy) | Crystal structure of E. coli MlaFB ABC transport subunits in the dimeric state | Descriptor: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Chang, Y, Bhabha, G, Ekiert, D.C. | Deposit date: | 2020-06-18 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Elife, 9, 2020
|
|
7UDL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7udl by Molmil](/molmil-images/mine/7udl) | Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide | Descriptor: | 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6 | Authors: | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
|
|
4R3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r3k by Molmil](/molmil-images/mine/4r3k) | |
4R3L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r3l by Molmil](/molmil-images/mine/4r3l) | |
7UE2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ue2 by Molmil](/molmil-images/mine/7ue2) | |
7UDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7udk by Molmil](/molmil-images/mine/7udk) | Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide | Descriptor: | 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4 | Authors: | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
|
|
7UDN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7udn by Molmil](/molmil-images/mine/7udn) | |
7UDM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7udm by Molmil](/molmil-images/mine/7udm) | Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide) | Descriptor: | 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6 | Authors: | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
|
|
7UPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7upq by Molmil](/molmil-images/mine/7upq) | |
7UPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7upo by Molmil](/molmil-images/mine/7upo) | |
7UPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7upp by Molmil](/molmil-images/mine/7upp) | |