7UDK

Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide

Summary for 7UDK

Entry DOI	10.2210/pdb7udk/pdb
Descriptor	Designed helical repeat protein (DHR) RPB_LRP2_R4, 4xLRP (2 entities in total)
Functional Keywords	peptide binding, designed helical repeat (dhr), de novo protein
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	21000.00
Authors	Chang, Y.,Redler, R.L.,Bhabha, G.,Ekiert, D.C. (deposition date: 2022-03-20, release date: 2023-03-22, Last modification date: 2024-04-03)
Primary citation	Wu, K.,Bai, H.,Chang, Y.T.,Redler, R.,McNally, K.E.,Sheffler, W.,Brunette, T.J.,Hicks, D.R.,Morgan, T.E.,Stevens, T.J.,Broerman, A.,Goreshnik, I.,DeWitt, M.,Chow, C.M.,Shen, Y.,Stewart, L.,Derivery, E.,Silva, D.A.,Bhabha, G.,Ekiert, D.C.,Baker, D. De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616:581-589, 2023 Cited by PubMed: 37020023 DOI: 10.1038/s41586-023-05909-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.18 Å)

Structure validation