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7YPL

Crystal structure of fibronectin type III domain variant, a VEGFR2-specific antagonist

Summary for 7YPL
Entry DOI10.2210/pdb7ypl/pdb
DescriptorFibronectin, SULFATE ION (3 entities in total)
Functional Keywordsfibronectin, fniii, vegfr2-specific antagonist, cell adhesion
Biological sourceHomo sapiens
Total number of polymer chains1
Total formula weight11498.83
Authors
Chang, Y.T.,Chen, C.Y.,Chuang, W.J. (deposition date: 2022-08-03, release date: 2023-08-16)
Primary citationChang, Y.S.,Katte, R.H.,Lin, C.C.,Chang, Y.T.,Chen, C.Y.,Chuang, W.J.
A Novel Disulfide Bond Engineering of Fibronectin Type III Domain Enhances Thermostability and Solubility of VEGFR2-Specific Antagonist
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.63 Å)
Structure validation

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