4W8P

Crystal structure of RIAM TBS1 in complex with talin R7R8 domains

Summary for 4W8P

Entry DOI	10.2210/pdb4w8p/pdb
Descriptor	Talin-1, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	talin, rod domains, r7r8, r8, riam, tbs1, peptide binding protein
Biological source	Mus musculus (Mouse) More
Cellular location	Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side : P26039 Cell membrane ; Peripheral membrane protein : Q8R5A3
Total number of polymer chains	2
Total formula weight	34128.39
Authors	Chang, Y.C.E.,Zhang, H.,Wu, J. (deposition date: 2014-08-25, release date: 2014-12-03, Last modification date: 2023-09-27)
Primary citation	Chang, Y.C.,Zhang, H.,Franco-Barraza, J.,Brennan, M.L.,Patel, T.,Cukierman, E.,Wu, J. Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling. Structure, 22:1810-1820, 2014 Cited by PubMed: 25465129 DOI: 10.1016/j.str.2014.09.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation