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PDB: 113 results

6XMF
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BU of 6xmf by Molmil
Cryo-EM structure of Cas12g binary complex
Descriptor: CRISPR-Cas, RNA (116-MER), ZINC ION
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2020-06-30
Release date:2021-01-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the RNA-guided ribonuclease Cas12g.
Nat.Chem.Biol., 17, 2021
6XMG
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BU of 6xmg by Molmil
Cryo-EM structure of Cas12g ternary complex
Descriptor: CRISPR-Cas, RNA (130-MER), RNA (5'-R(P*UP*UP*AP*AP*UP*GP*CP*GP*GP*UP*AP*GP*UP*UP*UP*AP*UP*CP*AP*CP*AP*GP*UP*U)-3'), ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2020-06-30
Release date:2021-01-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM structure of the RNA-guided ribonuclease Cas12g.
Nat.Chem.Biol., 17, 2021
4UI9
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BU of 4ui9 by Molmil
Atomic structure of the human Anaphase-Promoting Complex
Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
Authors:Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
Deposit date:2015-03-27
Release date:2015-06-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
6FX0
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BU of 6fx0 by Molmil
Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne
Descriptor: 6-[3-(1-adamantyl)-4-oxidanyl-phenyl]naphthalene-2-carboxylic acid, Retinoic acid receptor gamma, TETRAETHYLENE GLYCOL
Authors:Chantalat, L, Thoreau, E.
Deposit date:2018-03-08
Release date:2018-05-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne.
Bioorg. Med. Chem. Lett., 28, 2018
6OMV
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BU of 6omv by Molmil
CryoEM structure of the LbCas12a-crRNA-AcrVA4-DNA complex
Descriptor: AcrVA4, Cpf1, DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*GP*GP*A)-3'), ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2019-04-19
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
6NMD
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BU of 6nmd by Molmil
cryo-EM Structure of the LbCas12a-crRNA-AcrVA1 complex
Descriptor: AcrVA1, Cpf1, MAGNESIUM ION, ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2019-01-10
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
6NMA
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BU of 6nma by Molmil
CryoEM structure of the LbCas12a-crRNA-AcrVA4 complex
Descriptor: AcrVA1, Cpf1, MAGNESIUM ION, ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2019-01-10
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
6NME
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BU of 6nme by Molmil
Structure of LbCas12a-crRNA
Descriptor: Cpf1, MAGNESIUM ION, crRNA
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2019-01-10
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (5.67 Å)
Cite:Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
6NM9
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BU of 6nm9 by Molmil
CryoEM structure of the LbCas12a-crRNA-AcrVA4 dimer
Descriptor: AcrVA4, Cpf1, MAGNESIUM ION, ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2019-01-10
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
6NMC
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BU of 6nmc by Molmil
CryoEM structure of the LbCas12a-crRNA-2xAcrVA1 complex
Descriptor: AcrVA1, Cpf1, MAGNESIUM ION, ...
Authors:Chang, L, Li, Z, Zhang, H.
Deposit date:2019-01-10
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
1HGU
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BU of 1hgu by Molmil
HUMAN GROWTH HORMONE
Descriptor: HUMAN GROWTH HORMONE
Authors:Chantalat, L, Jones, N, Korber, F, Navaza, J, Pavlovsky, A.G.
Deposit date:1995-05-11
Release date:1995-12-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:THE CRYSTAL-STRUCTURE OF WILD-TYPE GROWTH-HORMONE AT 2.5 ANGSTROM RESOLUTION.
Protein Pept.Lett., 2, 1995
1HQ3
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BU of 1hq3 by Molmil
CRYSTAL STRUCTURE OF THE HISTONE-CORE-OCTAMER IN KCL/PHOSPHATE
Descriptor: CHLORIDE ION, HISTONE H2A-IV, HISTONE H2B, ...
Authors:Chantalat, L, Nicholson, J.M, Lambert, S.J, Reid, A.J, Donovan, M.J, Reynolds, C.D, Wood, C.M, Baldwin, J.P.
Deposit date:2000-12-14
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the histone-core octamer in KCl/phosphate crystals at 2.15 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
6TGB
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BU of 6tgb by Molmil
CryoEM structure of the binary DOCK2-ELMO1 complex
Descriptor: Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1
Authors:Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D.
Deposit date:2019-11-15
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
6TGC
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BU of 6tgc by Molmil
CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex.
Descriptor: Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1
Authors:Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D.
Deposit date:2019-11-15
Release date:2020-07-29
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
8FCJ
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BU of 8fcj by Molmil
Cryo-EM structure of Cascade-DNA (P23) complex in type I-B CAST system
Descriptor: Non-target DNA strand, RNA, Target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCU
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BU of 8fcu by Molmil
Cryo-EM structure of Cascade-DNA-TniQ-TnsC complex in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCX
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BU of 8fcx by Molmil
Cryo-EM structure of TnsC oligomer in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TnsC
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FD3
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BU of 8fd3 by Molmil
Cryo-EM structure of Cascade-PAM complex in type I-B CAST system
Descriptor: Non-target DNA strand, RNA, Target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCV
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BU of 8fcv by Molmil
Cryo-EM structure of TnsC-TniQ-DNA complex in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (60-MER), MAGNESIUM ION, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FF5
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BU of 8ff5 by Molmil
Cryo-EM structure of Cascade-DNA-fullRloop in type I-B CAST system
Descriptor: Non-target DNA strand, Nostoc sp. 'Peltigera membranacea cyanobiont' 210A, RNA, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-07
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCW
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BU of 8fcw by Molmil
Cryo-EM structure of TnsC-DNA complex in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (60-MER), MAGNESIUM ION, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FF4
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BU of 8ff4 by Molmil
Cryo-EM structure of Cascade-DNA-TniQ-TnsC complex (composite) in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-07
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
7N3O
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BU of 7n3o by Molmil
Cryo-EM structure of the Cas12k-sgRNA complex
Descriptor: Cas12k, Single guide RNA
Authors:Chang, L, Li, Z, Xiao, R, Wang, S, Han, R.
Deposit date:2021-06-01
Release date:2021-09-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition.
Mol.Cell, 81, 2021
7N3P
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BU of 7n3p by Molmil
Cryo-EM structure of the Cas12k-sgRNA-dsDNA complex
Descriptor: Cas12k, DNA (5'-D(*CP*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*AP*AP*CP*CP*GP*AP*GP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*CP*TP*CP*GP*GP*TP*T)-3'), ...
Authors:Chang, L, Li, Z, Xiao, R, Wang, S, Han, R.
Deposit date:2021-06-01
Release date:2021-09-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition.
Mol.Cell, 81, 2021
1QF8
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BU of 1qf8 by Molmil
TRUNCATED FORM OF CASEIN KINASE II BETA SUBUNIT (2-182) FROM HOMO SAPIENS
Descriptor: CASEIN KINASE II, MAGNESIUM ION, ZINC ION
Authors:Chantalat, L, Leroy, D, Filhol, O, Nueda, A, Benitez, M.J, Chambaz, E, Cochet, C, Dideberg, O.
Deposit date:1999-04-07
Release date:2000-04-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization.
EMBO J., 18, 1999

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