7N3O

Cryo-EM structure of the Cas12k-sgRNA complex

Summary for 7N3O

Entry DOI	10.2210/pdb7n3o/pdb
EMDB information	24142
Descriptor	Cas12k, Single guide RNA (2 entities in total)
Functional Keywords	crispr cas, rna binding protein, protein-rna complex, rna binding protein-rna complex, rna binding protein/rna
Biological source	Scytonema hofmannii More
Total number of polymer chains	2
Total formula weight	158541.97
Authors	Chang, L.,Li, Z.,Xiao, R.,Wang, S.,Han, R. (deposition date: 2021-06-01, release date: 2021-09-01, Last modification date: 2024-05-29)
Primary citation	Xiao, R.,Wang, S.,Han, R.,Li, Z.,Gabel, C.,Mukherjee, I.A.,Chang, L. Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition. Mol.Cell, 81:4457-4466.e5, 2021 Cited by PubMed: 34450043 DOI: 10.1016/j.molcel.2021.07.043 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation