6TGB
CryoEM structure of the binary DOCK2-ELMO1 complex
Summary for 6TGB
Entry DOI | 10.2210/pdb6tgb/pdb |
EMDB information | 10497 |
Descriptor | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 (2 entities in total) |
Functional Keywords | guanine nucleotide exchange factor, cytoskeleton, actin, cryoem, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 475696.36 |
Authors | Chang, L.,Yang, J.,Chang, J.H.,Zhang, Z.,Boland, A.,McLaughlin, S.H.,Abu-Thuraia, A.,Killoran, R.C.,Smith, M.J.,Cote, J.F.,Barford, D. (deposition date: 2019-11-15, release date: 2020-07-29) |
Primary citation | Chang, L.,Yang, J.,Jo, C.H.,Boland, A.,Zhang, Z.,McLaughlin, S.H.,Abu-Thuraia, A.,Killoran, R.C.,Smith, M.J.,Cote, J.F.,Barford, D. Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state. Nat Commun, 11:3464-3464, 2020 Cited by PubMed: 32651375DOI: 10.1038/s41467-020-17271-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.5 Å) |
Structure validation
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