6TGB

CryoEM structure of the binary DOCK2-ELMO1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002277	biological_process	myeloid dendritic cell activation involved in immune response
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0005096	molecular_function	GTPase activator activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005886	cellular_component	plasma membrane
A	0007264	biological_process	small GTPase-mediated signal transduction
A	0007520	biological_process	myoblast fusion
A	0012505	cellular_component	endomembrane system
A	0016020	cellular_component	membrane
A	0016477	biological_process	cell migration
A	0030036	biological_process	actin cytoskeleton organization
A	0031267	molecular_function	small GTPase binding
A	0035580	cellular_component	specific granule lumen
A	0042608	molecular_function	T cell receptor binding
A	0044351	biological_process	macropinocytosis
A	0050766	biological_process	positive regulation of phagocytosis
A	0051056	biological_process	regulation of small GTPase mediated signal transduction
A	0070062	cellular_component	extracellular exosome
B	0005085	molecular_function	guanyl-nucleotide exchange factor activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006909	biological_process	phagocytosis
B	0006911	biological_process	phagocytosis, engulfment
B	0006915	biological_process	apoptotic process
B	0007015	biological_process	actin filament organization
B	0016020	cellular_component	membrane
B	0016601	biological_process	Rac protein signal transduction
B	0017124	molecular_function	SH3 domain binding
B	0030036	biological_process	actin cytoskeleton organization
B	0032045	cellular_component	guanyl-nucleotide exchange factor complex
B	0048870	biological_process	cell motility
B	0098794	cellular_component	postsynapse
B	0098978	cellular_component	glutamatergic synapse
B	0150052	biological_process	regulation of postsynapse assembly
B	0160124	molecular_function	guanyl nucleotide exchange factor activator activity
B	2001212	biological_process	regulation of vasculogenesis
D	0002277	biological_process	myeloid dendritic cell activation involved in immune response
D	0005085	molecular_function	guanyl-nucleotide exchange factor activity
D	0005096	molecular_function	GTPase activator activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005886	cellular_component	plasma membrane
D	0007264	biological_process	small GTPase-mediated signal transduction
D	0007520	biological_process	myoblast fusion
D	0012505	cellular_component	endomembrane system
D	0016020	cellular_component	membrane
D	0016477	biological_process	cell migration
D	0030036	biological_process	actin cytoskeleton organization
D	0031267	molecular_function	small GTPase binding
D	0035580	cellular_component	specific granule lumen
D	0042608	molecular_function	T cell receptor binding
D	0044351	biological_process	macropinocytosis
D	0050766	biological_process	positive regulation of phagocytosis
D	0051056	biological_process	regulation of small GTPase mediated signal transduction
D	0070062	cellular_component	extracellular exosome

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Motif: {"description":"SH3-binding"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Modified residue: {"description":"Phosphotyrosine; by HCK","evidences":[{"source":"PubMed","id":"15952790","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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