4A9O
 
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5 ethyl-3-methyl-4-phenyl-1, 2-oxazole | | 分子名称: | 1,2-ETHANEDIOL, 5-ETHYL-3-METHYL-4-PHENYL-1,2-OXAZOLE, BROMODOMAIN CONTAINING 2, ... | | 著者 | Chung, C.W, Bamborough, P. | | 登録日 | 2011-11-26 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides.
J.Med.Chem., 55, 2012
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4ALH
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3,5 dimethyl-4-phenyl-1,2- oxazole | | 分子名称: | 1,2-ETHANEDIOL, 3,5 DIMETHYL-4-PHENYL-1,2-OXAZOLE, BROMODOMAIN CONTAINING 2, ... | | 著者 | Chung, C.W, Bamborough, P. | | 登録日 | 2012-03-03 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides.
J.Med.Chem., 55, 2012
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4A9J
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4B6F
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (4-phenoxyphenyl)methylazanium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, ... | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-09 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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5H1Z
 | | CYP153D17 from Sphingomonas sp. PAMC 26605 | | 分子名称: | DODECANE, PROTOPORPHYRIN IX CONTAINING FE, putative CYP alkane hydroxylase CYP153D17 | | 著者 | Lee, C.W, Lee, J.H. | | 登録日 | 2016-10-13 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structure of a Putative Cytochrome P450 Alkane Hydroxylase (CYP153D17) from Sphingomonas sp. PAMC 26605 and Its Conformational Substrate Binding
Int J Mol Sci, 17, 2016
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4A9K
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4AMP
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4AMN
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4AOW
 | | Crystal structure of the human Rack1 protein at a resolution of 2.45 angstrom | | 分子名称: | GLYCEROL, GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-2-LIKE 1 | | 著者 | Ruiz Carrillo, D, Chandrasekaran, R, Nilsson, M, Cornvick, T, Liew, C.W, Tan, S.M, Lescar, J. | | 登録日 | 2012-03-30 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of Human Rack1 Protein at a Resolution of 2.45 A.
Acta Crystallogr.,Sect.F, 68, 2012
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5GWG
 | | Solution structure of rattusin | | 分子名称: | Defensin alpha-related sequence 1 | | 著者 | Lee, C.W, Min, H.J. | | 登録日 | 2016-09-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rattusin structure reveals a novel defensin scaffold formed by intermolecular disulfide exchanges
Sci Rep, 7, 2017
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4B75
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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3L86
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5FJ9
 | | Cryo-EM structure of yeast apo RNA polymerase III at 4.6 A | | 分子名称: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2, ... | | 著者 | Hoffmann, N.A, Jakobi, A.J, Moreno-Morcillo, M, Glatt, S, Kosinski, J, Hagen, W.J, Sachse, C, Muller, C.W. | | 登録日 | 2015-10-06 | | 公開日 | 2015-11-25 | | 最終更新日 | 2019-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Molecular Structures of Unbound and Transcribing RNA Polymerase III.
Nature, 528, 2015
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4B73
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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4AMM
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4B76
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, [2,4-bis(fluoranyl)-3-phenoxy-phenyl]methylazanium | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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5E3E
 | | Crystal structure of CdiA-CT/CdiI complex from Y. kristensenii 33638 | | 分子名称: | CdiI immunity protein, Large exoprotein involved in heme utilization or adhesion, SODIUM ION | | 著者 | Michalska, K, Joachimiak, G, Jedrzejczak, R, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-10-02 | | 公開日 | 2015-11-25 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily.
Nucleic Acids Res., 45, 2017
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4BJI
 | | Sfc1-DBD | | 分子名称: | TRANSCRIPTION FACTOR TAU SUBUNIT SFC1 | | 著者 | Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. | | 登録日 | 2013-04-18 | | 公開日 | 2013-07-31 | | 最終更新日 | 2013-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74.
Nucleic Acids Res., 41, 2013
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4B74
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (2S)-4-[(2-ammonioethyl)amino]-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function
Nat.Chem.Biol., 8, 2012
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5FJ8
 | | Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 A | | 分子名称: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2, ... | | 著者 | Hoffmann, N.A, Jakobi, A.J, Moreno-Morcillo, M, Glatt, S, Kosinski, J, Hagen, W.J, Sachse, C, Muller, C.W. | | 登録日 | 2015-10-06 | | 公開日 | 2015-11-25 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular Structures of Unbound and Transcribing RNA Polymerase III.
Nature, 528, 2015
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3HX9
 | | Structure of heme-degrader, MhuD (Rv3592), from Mycobacterium tuberculosis with two hemes bound in its active site | | 分子名称: | CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Protein Rv3592 | | 著者 | Chim, N, Nguyen, T.Q, Iniguez, A, Goulding, C.W. | | 登録日 | 2009-06-19 | | 公開日 | 2009-12-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Unusual Diheme Conformation of the Heme-Degrading Protein from Mycobacterium tuberculosis
J.Mol.Biol., 395, 2009
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5HKQ
 | | Crystal structure of CDI complex from Escherichia coli STEC_O31 | | 分子名称: | CdiI immunity protein, Contact-dependent inhibitor A | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-01-14 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-03-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Functional plasticity of antibacterial EndoU toxins.
Mol.Microbiol., 109, 2018
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4B71
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propan-1-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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4B6E
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | 1H-indazol-7-amine, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, ... | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-09 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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3KVF
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