Summary for 4ALH
Entry DOI | 10.2210/pdb4alh/pdb |
Related | 1X0J 2YDW 2YEK 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN |
Descriptor | BROMODOMAIN CONTAINING 2, 1,2-ETHANEDIOL, 3,5 DIMETHYL-4-PHENYL-1,2-OXAZOLE, ... (5 entities in total) |
Functional Keywords | signaling protein-inhibitor complex, histone, epigenetic reader, signaling protein/inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 3 |
Total formula weight | 54754.20 |
Authors | Chung, C.W.,Bamborough, P. (deposition date: 2012-03-03, release date: 2012-04-11, Last modification date: 2019-05-15) |
Primary citation | Bamborough, P.,Diallo, H.,Goodacre, J.D.,Gordon, L.,Lewis, A.,Seal, J.T.,Wilson, D.M.,Woodrow, M.D.,Chung, C.W. Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides. J.Med.Chem., 55:587-, 2012 Cited by PubMed: 22136469DOI: 10.1021/JM201283Q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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