2VX0
| ephB4 kinase domain inhibitor complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION, N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3-MORPHOLIN-4-YLPHENYL)PYRIMIDINE-2,4-DIAMINE | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D, Leach, A.G, Kettle, J.G. | 登録日 | 2008-06-30 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inhibitors of the Tyrosine Kinase Ephb4. Part 1: Structure-Based Design and Optimization of a Series of 2,4-Bis-Anilinopyrimidines. Bioorg.Med.Chem.Lett., 18, 2008
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2VWX
| ephB4 kinase domain inhibitor complex | 分子名称: | 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide, EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D, Leach, A.G, Kettle, J.G. | 登録日 | 2008-06-27 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Inhibitors of the Tyrosine Kinase Ephb4. Part 2: Structure-Based Discovery and Optimisation of 3,5-Bis Substituted Anilinopyrimidines. Bioorg.Med.Chem.Lett., 18, 2008
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5OC0
| Structure of E. coli superoxide oxidase | 分子名称: | Cytochrome b561, GLYCEROL, MAGNESIUM ION, ... | 著者 | Lundgren, C.A.K, Sjostrand, D, Biner, O, Bennett, M, von Ballmoos, C, Hogbom, M. | 登録日 | 2017-06-29 | 公開日 | 2018-06-20 | 最終更新日 | 2018-11-07 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Scavenging of superoxide by a membrane-bound superoxide oxidase. Nat. Chem. Biol., 14, 2018
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2VWV
| ephB4 kinase domain inhibitor complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 4, N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Kettle, J.G, Leach, A.G. | 登録日 | 2008-06-27 | 公開日 | 2008-07-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibitors of the Tyrosine Kinase Ephb4. Part 1: Structure-Based Design and Optimization of a Series of 2,4-Bis-Anilinopyrimidines Bioorg.Med.Chem.Lett., 18, 2008
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3M4Z
| Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site | 分子名称: | CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ... | 著者 | Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M. | 登録日 | 2010-03-12 | 公開日 | 2010-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase To be Published
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2VV9
| CDK2 in complex with an imidazole piperazine | 分子名称: | 2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol, CELL DIVISION PROTEIN KINASE 2 | 著者 | Acton, D.G, Anderson, M, Andrews, D.M, Barker, A.J, Brassington, C.A, Finlay, M.R, Fisher, E, Gerhardt, S, Graham, M.A, Green, C.P, Heaton, D.W, Loddick, S.A, Morgentin, R, Read, J, Roberts, A, Stanway, J, Tucker, J.A, Weir, H.M. | 登録日 | 2008-06-04 | 公開日 | 2008-08-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Imidazole Piperazines: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors with a Novel Binding Mode. Bioorg.Med.Chem.Lett., 18, 2008
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1Y7N
| Solution structure of the second PDZ domain of the human neuronal adaptor X11alpha | 分子名称: | Amyloid beta A4 precursor protein-binding family A member 1 | 著者 | Duquesne, A.E, de Ruijter, M, Brouwer, J, Drijfhout, J.W, Nabuurs, S.B, Spronk, C.A.E.M, Vuister, G.W, Ubbink, M, Canters, G.W. | 登録日 | 2004-12-09 | 公開日 | 2005-11-22 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the second PDZ domain of the neuronal adaptor X11alpha and its interaction with the C-terminal peptide of the human copper chaperone for superoxide dismutase J.Biomol.Nmr, 32, 2005
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5OEO
| Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant | 分子名称: | CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5 | 著者 | Vuister, G.W, Bokhovchuk, F.M, Bate, N, Kovalevskaya, N, Goult, B.T, Spronk, C.A.E.M. | 登録日 | 2017-07-09 | 公開日 | 2018-04-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel. Biochemistry, 57, 2018
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5OH5
| Legionella pneumophila RidL N-terminal retromer binding domain | 分子名称: | RidL | 著者 | Baerlocher, K, Hutter, C.A.J, Swart, A.L, Steiner, B, Welin, A, Hohl, M, Letourneur, F, Seeger, M.A, Hilbi, H. | 登録日 | 2017-07-14 | 公開日 | 2017-11-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5. Nat Commun, 8, 2017
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1C94
| REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD. | 分子名称: | RETRO-GCN4 LEUCINE ZIPPER | 著者 | Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G. | 登録日 | 1999-07-30 | 公開日 | 2000-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure. Proc.Natl.Acad.Sci.USA, 97, 2000
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3PAZ
| REDUCED NATIVE PSEUDOAZURIN FROM A. FAECALIS | 分子名称: | COPPER (II) ION, PSEUDOAZURIN | 著者 | Adman, E.T, Libeu, C.A.P. | 登録日 | 1997-02-20 | 公開日 | 1997-08-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Site-directed mutants of pseudoazurin: explanation of increased redox potentials from X-ray structures and from calculation of redox potential differences. Biochemistry, 36, 1997
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7JJA
| Crystal structure of the ZinT-like domain of Streptococcus pneumoniae AdcA in the apo form | 分子名称: | SODIUM ION, Zinc-binding lipoprotein AdcA, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA. Mbio, 12, 2021
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3MLM
| Crystal structure of Bn IV in complex with myristic acid: A Lys49 myotoxic phospholipase A2 from Bothrops neuwiedi venom | 分子名称: | BN-IV Lys-49 Phospholipase A2, MYRISTIC ACID, SULFATE ION | 著者 | Delatorre, P, Rocha, B.A.M, Cavada, B.S, Toyama, M.H, Toyama, D, Gadelha, C.A.A. | 登録日 | 2010-04-17 | 公開日 | 2011-05-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structure of Bn IV in complex with myristic acid: a Lys49 myotoxic phospholipase A2 from Bothrops neuwiedi venom. Biochimie, 93, 2011
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2X9F
| ephB4 kinase domain inhibitor complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION, N^4^-1H-INDAZOL-4-YL-N^2^-[3-(METHYLSULFONYL)PHENYL]PYRIMIDINE-2,4-DIAMINE | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D. | 登録日 | 2010-03-17 | 公開日 | 2010-09-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Inhibitors of the Tyrosine Kinase Ephb4. Part 3: Identification of Non-Benzodioxole-Based Kinase Inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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7JJ9
| Crystal structure of Zn(II)-bound AdcA from Streptococcus pneumoniae | 分子名称: | CHLORIDE ION, ZINC ION, Zinc-binding lipoprotein AdcA | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA. Mbio, 12, 2021
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7JJ8
| Crystal structure of the Zn(II)-bound ZnuA-like domain of Streptococcus pneumoniae AdcA | 分子名称: | ZINC ION, Zinc-binding lipoprotein AdcA | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA. Mbio, 12, 2021
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7JIS
| HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 2F | 分子名称: | (3S)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]-3-methyl-1,3-dihydro-2H-indol-2-one, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 著者 | Lesburg, C.A, Augustin, M. | 登録日 | 2020-07-23 | 公開日 | 2020-12-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Optimization of Versatile Oxindoles as Selective PI3K delta Inhibitors. Acs Med.Chem.Lett., 11, 2020
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7JJB
| Crystal structure of Zn(II)-bound ZinT-like domain of Streptococcus pneumoniae AdcA | 分子名称: | MAGNESIUM ION, SODIUM ION, ZINC ION, ... | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA. Mbio, 12, 2021
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7JIU
| HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 2F | 分子名称: | (3S)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]-3-methyl-1,3-dihydro-2H-indol-2-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Lesburg, C.A, Augustin, M. | 登録日 | 2020-07-23 | 公開日 | 2021-06-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Optimization of Versatile Oxindoles as Selective PI3K delta Inhibitors. Acs Med.Chem.Lett., 11, 2020
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3OER
| Crystal structure of trimeric frataxin from the yeast saccharomyces cerevisiae, complexed with cobalt | 分子名称: | COBALT (II) ION, Frataxin homolog, mitochondrial | 著者 | Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S. | 登録日 | 2010-08-13 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering. J.Mol.Biol., 414, 2011
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3OEQ
| Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, with full length n-terminus | 分子名称: | Frataxin homolog, mitochondrial | 著者 | Soderberg, C.A.G, Rajan, S, Gakh, O, Ta, C, Isaya, G, Al-Karadaghi, S. | 登録日 | 2010-08-13 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering. J.Mol.Biol., 414, 2011
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1XB1
| The Structure of the BIR domain of IAP-like protein 2 | 分子名称: | Baculoviral IAP repeat-containing protein 8, Diablo homolog, mitochondrial, ... | 著者 | Shin, H, Renatus, M, Eckelman, B.P, Nunes, V.A, Sampaio, C.A.M, Salvesen, G.S. | 登録日 | 2004-08-27 | 公開日 | 2004-11-02 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition Biochem.J., 385, 2005
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2A74
| Human Complement Component C3c | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Complement Component C3c, GLYCEROL, ... | 著者 | Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P. | 登録日 | 2005-07-04 | 公開日 | 2005-09-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of complement component C3 provide insights into the function and evolution of immunity. Nature, 437, 2005
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2A73
| Human Complement Component C3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P. | 登録日 | 2005-07-04 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of complement component C3 provide insights into the function and evolution of immunity. Nature, 437, 2005
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1VJH
| Crystal structure of gene product of At1g24000 from Arabidopsis thaliana | 分子名称: | Bet v I allergen family | 著者 | Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2004-02-20 | 公開日 | 2004-03-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 1H, 15N and 13C resonance assignments of the putative Bet v 1 family protein At1g24000.1 from Arabidopsis thaliana. J.Biomol.Nmr, 32, 2005
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