1XB1

The Structure of the BIR domain of IAP-like protein 2

Summary for 1XB1

• Entry DOI: 10.2210/pdb1xb1/pdb
• Related: 1XB0
• Descriptor: Baculoviral IAP repeat-containing protein 8, Diablo homolog, mitochondrial, ZINC ION, ... (4 entities in total)
• Functional Keywords: apoptosis, iap, caspase inhibition, smac, diabolo
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (Probable): Q96P09; Mitochondrion: Q9NR28
• Total number of polymer chains: 12
• Total formula weight: 79965.16

Authors

Shin, H.,Renatus, M.,Eckelman, B.P.,Nunes, V.A.,Sampaio, C.A.M.,Salvesen, G.S. (deposition date: 2004-08-27, release date: 2004-11-02, Last modification date: 2011-07-13)

• Primary citation: Shin, H.,Renatus, M.,Eckelman, B.P.,Nunes, V.A.,Sampaio, C.A.M.,Salvesen, G.S.; The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition; Biochem.J., 385:1-10, 2005; PubMed: 15485395; DOI: 10.1042/BJ20041107

Experimental method

X-RAY DIFFRACTION (2.7 Å)