1XB1

The Structure of the BIR domain of IAP-like protein 2

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 400

Chain	Residue
A	GLU333
B	HOH70
F	HIS336

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	HIS302
A	GLU332
B	HOH149

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 402

Chain	Residue
C	GLU295
A	GLU266
B	HIS343
B	THR356

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 403

Chain	Residue
A	CYS300
A	CYS303
A	HIS320
A	CYS327

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 500

Chain	Residue
B	HIS302
B	GLU332
E	GLU349

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 501

Chain	Residue
B	GLU266
C	HIS343

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 502

Chain	Residue
B	GLU333
E	HOH156
E	HIS336

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 600

Chain	Residue
C	GLU333
D	HIS336

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 601

Chain	Residue
C	HOH46
C	HIS302
C	GLU332

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 602

Chain	Residue
C	GLU266
D	HIS343

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 603

Chain	Residue
C	CYS300
C	CYS303
C	HIS320
C	CYS327

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN D 700

Chain	Residue
C	HIS336
D	GLU333

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN D 701

Chain	Residue
D	HIS302
D	GLU332

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN E 702

Chain	Residue
D	GLU266
E	HIS343
E	THR356

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 703

Chain	Residue
D	CYS300
D	CYS303
D	HIS320
D	CYS327

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN E 800

Chain	Residue
B	HIS336
E	GLU333

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN E 801

Chain	Residue
B	GLU349
E	HIS302
E	GLU332

---

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN F 802

Chain	Residue
E	HOH9
E	GLU266
F	HIS343

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 803

Chain	Residue
E	CYS300
E	CYS303
E	HIS320
E	CYS327

---

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN F 900

Chain	Residue
A	HIS336
F	GLU333

---

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN F 901

Chain	Residue
F	HIS302
F	GLU332

---

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 902

Chain	Residue
A	HIS343
F	HOH39
F	GLU266

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 903

Chain	Residue
F	CYS300
F	CYS303
F	HIS320
F	CYS327

---

Functional Information from PROSITE/UniProt

site_id	PS01282
Number of Residues	66
Details	BIR_REPEAT_1 BIR repeat. YeaRlitfgt.Wmysvnkeqlar...AGFyAigqeDkvqCfhCggglanWkpkedpweqHakwyPgCkyL

Chain	Residue	Details
A	TYR265-LEU330

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	378
Details	Repeat: {"description":"BIR"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00029","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Motif: {"description":"IAP-binding"}

Chain

Residue

Details

---