2X9F
ephB4 kinase domain inhibitor complex
Summary for 2X9F
Entry DOI | 10.2210/pdb2x9f/pdb |
Related | 2BBA 2VWU 2VWV 2VWW 2VWX 2VWY 2VWZ 2VX0 2VX1 |
Descriptor | EPHRIN TYPE-B RECEPTOR 4, N^4^-1H-INDAZOL-4-YL-N^2^-[3-(METHYLSULFONYL)PHENYL]PYRIMIDINE-2,4-DIAMINE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | transferase, atp-binding, glycoprotein, transmembrane |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 34363.85 |
Authors | Read, J.,Brassington, C.A.,Green, I.,McCall, E.J.,Valentine, A.L.,Barratt, D. (deposition date: 2010-03-17, release date: 2010-09-29, Last modification date: 2023-12-20) |
Primary citation | Bardelle, C.,Barlaam, B.,Brooks, N.,Coleman, T.,Cross, D.,Ducray, R.,Green, I.,Brempt, C.L.,Olivier, A.,Read, J. Inhibitors of the Tyrosine Kinase Ephb4. Part 3: Identification of Non-Benzodioxole-Based Kinase Inhibitors. Bioorg.Med.Chem.Lett., 20:6242-, 2010 Cited by PubMed: 20850301DOI: 10.1016/J.BMCL.2010.08.100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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