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PDB: 141 results

2ISG
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BU of 2isg by Molmil
Botulinum Neurotoxin A Light Chain WT Crystal Form B
Descriptor: NICKEL (II) ION, Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T, Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISH
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Botulinum Neurotoxin A Light Chain WT Crystal Form C
Descriptor: Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T, Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISE
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Botulinum Neurotoxin A Light Chain WT Crystal Form A
Descriptor: Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T, Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
4PNJ
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BU of 4pnj by Molmil
Recombinant Sperm Whale P6 Myoglobin Solved with Single Pulse Free Electron Laser Data
Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Cohen, A, Gonzalez, A, Lam, W, Lyubimov, A, Sauter, N, Tsai, Y, Uervirojnangkoorn, M, Brunger, A, Soltis, M.
Deposit date:2014-05-23
Release date:2014-11-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 111, 2014
5W5C
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BU of 5w5c by Molmil
Crystal structure of the primed SNARE-Complexin-Synaptotagmin-1 C2AB complex
Descriptor: Complexin-1, GLYCEROL, MAGNESIUM ION, ...
Authors:Zhou, Q, Brunger, A.T.
Deposit date:2017-06-14
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.
Nature, 548, 2017
6MDO
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BU of 6mdo by Molmil
The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ...
Authors:White, K.I, Zhao, M, Brunger, A.T.
Deposit date:2018-09-04
Release date:2018-09-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
7RZU
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BU of 7rzu by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with A942S mutation
Descriptor: SARS-CoV-2 HR1 A942S linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZS
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BU of 7rzs by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with L938F mutation
Descriptor: SARS-CoV-2 HR1 L938F linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZR
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BU of 7rzr by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with D936Y mutation
Descriptor: SARS-CoV-2 HR1 D936Y linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZT
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BU of 7rzt by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with S940F mutation
Descriptor: SARS-CoV-2 HR1 S940F linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZV
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BU of 7rzv by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with V1176F mutation
Descriptor: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZQ
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BU of 7rzq by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex
Descriptor: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
1N0Y
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BU of 1n0y by Molmil
Crystal Structure of Pb-bound Calmodulin
Descriptor: ACETATE ION, CACODYLATE ION, Calmodulin, ...
Authors:Wilson, M.A, Brunger, A.T.
Deposit date:2002-10-15
Release date:2003-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Domain flexibility in the 1.75 A resolution structure of Pb2+-calmodulin.
Acta Crystallogr.,Sect.D, 59, 2003
1EDU
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BU of 1edu by Molmil
CRYSTAL STRUCTURE OF THE ENTH DOMAIN OF RAT EPSIN 1
Descriptor: 1,2-ETHANEDIOL, EH domain binding protein EPSIN
Authors:Hyman, J.H, Chen, H, Decamilli, P, Brunger, A.T.
Deposit date:2000-01-28
Release date:2000-05-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF).
J.Cell Biol., 149, 2000
3CF0
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BU of 3cf0 by Molmil
Structure of D2 subdomain of P97/VCP in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Davies, J.M, Brunger, A.T, Weis, W.I.
Deposit date:2008-03-01
Release date:2008-04-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change.
Structure, 16, 2008
8CZI
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BU of 8czi by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2
Descriptor: Scaffolded Spike protein S2' HR1, Spike protein S2' HR2
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-05-24
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.22 Å)
Cite:Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TIK
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BU of 7tik by Molmil
Structure of the SARS-CoV-2 Omicron spike post-fusion bundle
Descriptor: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-01-13
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FA2
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BU of 8fa2 by Molmil
Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex
Descriptor: Scaffolded Spike protein S2' HR1, Spike protein S2' 42G
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-11-25
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FA1
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BU of 8fa1 by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation
Descriptor: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2' HR2
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-11-25
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
9BRR
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BU of 9brr by Molmil
Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 2024
9BRA
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BU of 9bra by Molmil
Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 2024
9BRQ
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Intact V-ATPase State 3 and synaptophysin complex in mouse brain isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 2024
9BRU
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BU of 9bru by Molmil
Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 2024
9BRS
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BU of 9brs by Molmil
Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 2024
9BRT
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BU of 9brt by Molmil
Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 2024

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