Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 43 件
9BQV
DownloadVisualize
BU of 9bqv by Molmil
DdmD dimer apoprotein
分子名称: Helicase/UvrB N-terminal domain-containing protein
著者Bravo, J.P.K, Taylor, D.W.
登録日2024-05-10
公開日2024-07-03
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
4D7Z
DownloadVisualize
BU of 4d7z by Molmil
E. coli L-aspartate-alpha-decarboxylase mutant N72Q to a resolution of 1.9 Angstroms
分子名称: ASPARTATE 1-DECARBOXYLASE ALPHA CHAIN, ASPARTATE 1-DECARBOXYLASE BETA CHAIN, DI(HYDROXYETHYL)ETHER, ...
著者Bravo, J.P.K, Monteiro, D.C.F, Webb, M.E, Pearson, A.R.
登録日2014-12-02
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Structure of the E. Coli L-Aspartate-Alpha-Decarboxylase Mutant N72Q to a Resolution of 1.9 Angstroms
To be Published
7L1F
DownloadVisualize
BU of 7l1f by Molmil
SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate
分子名称: Non-structural protein 7, Non-structural protein 8, RNA (5'-R(P*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*UP*CP*UP*UP*AP*G)-3'), ...
著者Bravo, J.P.K, Taylor, D.W.
登録日2020-12-14
公開日2021-02-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication.
Mol.Cell, 81, 2021
7JHY
DownloadVisualize
BU of 7jhy by Molmil
Type IV-B CRISPR Complex
分子名称: Csf2 (Cas7), Csf4 (Cas11), RNA (31-MER)
著者Bravo, J.P.K, Taylor, D.W.
登録日2020-07-21
公開日2021-03-31
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of a type IV CRISPR-Cas ribonucleoprotein complex.
Iscience, 24, 2021
7PKO
DownloadVisualize
BU of 7pko by Molmil
CryoEM structure of Rotavirus NSP2
分子名称: Non-structural protein 2
著者Bravo, J.P.K, Borodavka, A.
登録日2021-08-26
公開日2021-09-29
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PKP
DownloadVisualize
BU of 7pkp by Molmil
NSP2 RNP complex
分子名称: Non-structural protein 2
著者Bravo, J.P.K, Borodavka, A.
登録日2021-08-26
公開日2021-09-29
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S4U
DownloadVisualize
BU of 7s4u by Molmil
Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, Target strand, ...
著者Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A.
登録日2021-09-09
公開日2022-03-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
7S4V
DownloadVisualize
BU of 7s4v by Molmil
Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation
分子名称: CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ...
著者Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A.
登録日2021-09-09
公開日2022-03-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
7S4X
DownloadVisualize
BU of 7s4x by Molmil
Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ...
著者Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A.
登録日2021-09-09
公開日2022-03-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
7S9V
DownloadVisualize
BU of 7s9v by Molmil
DrmAB:ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, DrmA, DrmB
著者Bravo, J.P.K, Taylor, D.W, Brouns, S.J.J, Aparicio-Maldonado, C.
登録日2021-09-21
公開日2022-06-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for broad anti-phage immunity by DISARM.
Nat Commun, 13, 2022
7S9W
DownloadVisualize
BU of 7s9w by Molmil
Structure of DrmAB:ADP:DNA complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DrmA, ...
著者Bravo, J.P.K, Taylor, D.W, Brounds, S.J.J, Aparicio-Maldonado, C.
登録日2021-09-21
公開日2022-06-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for broad anti-phage immunity by DISARM.
Nat Commun, 13, 2022
8TZZ
DownloadVisualize
BU of 8tzz by Molmil
SpG Cas9 with NGC PAM DNA target
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ...
著者Bravo, J.P.K, Hibshman, G.N, Taylor, D.W.
登録日2023-08-28
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
8U3Y
DownloadVisualize
BU of 8u3y by Molmil
SpG Cas9 with NGG PAM DNA target
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ...
著者Bravo, J.P.K, Hibshman, G.N, Taylor, D.W.
登録日2023-09-08
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
8U0J
DownloadVisualize
BU of 8u0j by Molmil
DdmE in complex with guide and target DNA
分子名称: DNA (5'-D(P*AP*CP*TP*TP*AP*AP*AP*GP*TP*CP*TP*AP*AP*CP*CP*TP*AP*TP*AP*GP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*CP*TP*AP*TP*AP*GP*GP*A)-3'), DNA (5'-D(P*GP*TP*TP*AP*GP*AP*CP*TP*TP*TP*AP*AP*GP*T)-3'), ...
著者Bravo, J.P.K.
登録日2023-08-29
公開日2024-07-03
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
8U0W
DownloadVisualize
BU of 8u0w by Molmil
DdmD monomer in complex with ssDNA
分子名称: DNA (5'-D(P*TP*TP*AP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Helicase/UvrB N-terminal domain-containing protein
著者Bravo, J.P.K.
登録日2023-08-29
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
8U0U
DownloadVisualize
BU of 8u0u by Molmil
DdmD dimer in complex with ssDNA
分子名称: DNA (5'-D(P*TP*TP*AP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Helicase/UvrB N-terminal domain-containing protein
著者Bravo, J.P.K.
登録日2023-08-29
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
8U3K
DownloadVisualize
BU of 8u3k by Molmil
DdmDE handover complex
分子名称: DNA (29-MER), DNA (5'-D(P*GP*GP*AP*AP*AP*TP*GP*TP*TP*GP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
著者Bravo, J.P.K.
登録日2023-09-07
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
8UMF
DownloadVisualize
BU of 8umf by Molmil
Structure of PsCas9 in complex with gRNA and DNA in product state
分子名称: Cas9, DNA (80-MER), MAGNESIUM ION, ...
著者Bravo, J.P.K, Taylor, D.W.
登録日2023-10-17
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure-guided engineering of PsCas9 yields a high fidelity and activity enzyme for in vivo gene editing
To Be Published
8D4A
DownloadVisualize
BU of 8d4a by Molmil
Cas12a2 quaternary complex
分子名称: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Bravo, J.P.K, Taylor, D.W.
登録日2022-06-01
公開日2023-01-18
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
8D49
DownloadVisualize
BU of 8d49 by Molmil
Structure of Cas12a2 binary complex
分子名称: OrfB_Zn_ribbon domain-containing protein, RNA (26-MER)
著者Bravo, J.P.K, Taylor, D.W.
登録日2022-06-01
公開日2023-01-18
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
8D4B
DownloadVisualize
BU of 8d4b by Molmil
Structure of Cas12a2 ternary complex
分子名称: OrfB_Zn_ribbon domain-containing protein, RNA (28-MER), RNA (41-MER)
著者Bravo, J.P.K, Taylor, D.W.
登録日2022-06-01
公開日2023-01-18
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
8TL0
DownloadVisualize
BU of 8tl0 by Molmil
Structure of activated SAVED-CHAT filament
分子名称: CHAT domain-containing protein, RNA (5'-R(*AP*AP*A)-3')
著者Bravo, J.P.K, Taylor, D.W.
登録日2023-07-26
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Science, 383, 2024
7UG6
DownloadVisualize
BU of 7ug6 by Molmil
Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W.
登録日2022-03-24
公開日2022-12-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome.
Nat.Struct.Mol.Biol., 30, 2023
7KHA
DownloadVisualize
BU of 7kha by Molmil
Cryo-EM Structure of the Desulfovibrio vulgaris Type I-C Apo Cascade
分子名称: CRISPR-associated protein, CT1133 family, CT1134 family, ...
著者O'Brien, R, Wrapp, D, Bravo, J.P.K, Schwartz, E, Taylor, D.
登録日2020-10-20
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for assembly of non-canonical small subunits into type I-C Cascade.
Nat Commun, 11, 2020
8DFS
DownloadVisualize
BU of 8dfs by Molmil
type I-C Cascade bound to AcrIF2
分子名称: Anti-CRISPR protein 30, CRISPR-associated protein, CT1133 family, ...
著者O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.
登録日2022-06-22
公開日2023-02-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023

 

12>

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon