8UMF
Structure of PsCas9 in complex with gRNA and DNA in product state
Summary for 8UMF
Entry DOI | 10.2210/pdb8umf/pdb |
EMDB information | 42378 |
Descriptor | Cas9, RNA (121-MER), DNA (80-MER), ... (5 entities in total) |
Functional Keywords | cas9, crispr, immune system |
Biological source | Parasutterella secunda More |
Total number of polymer chains | 5 |
Total formula weight | 284207.26 |
Authors | Bravo, J.P.K.,Taylor, D.W. (deposition date: 2023-10-17, release date: 2024-10-02, Last modification date: 2025-05-14) |
Primary citation | Bravo, J.P.K.,Taylor, D.W. Structure-guided engineering of PsCas9 yields a high fidelity and activity enzyme for in vivo gene editing To Be Published, |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
Download full validation report
