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PDB: 202 results
5UEM
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BU of 5uem by Molmil
Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 354NC37 Fab Heavy Chain, ...
Authors:Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
Deposit date:2017-01-02
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
7UGM
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BU of 7ugm by Molmil
Crystal Structure of BG24-iGL CDR3mat Fab
Descriptor: BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGQ
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BU of 7ugq by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGP
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BU of 7ugp by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
6MEG
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BU of 6meg by Molmil
Crystal structure of human monoclonal antibody HEPC46
Descriptor: antibody HEPC46 Heavy Chain, antibody HEPC46 Light Chain
Authors:Flyak, A.I, Bjorkman, P.J.
Deposit date:2018-09-06
Release date:2018-11-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
7UGO
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BU of 7ugo by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UZA
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BU of 7uza by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-1 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ5
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BU of 7uz5 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-6 Fab heavy chain, M8a-6 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZB
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BU of 7uzb by Molmil
Structure of the SARS-CoV-2 S S1 doamin in complex with the mouse antibody Fab fragment, HSW-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-2 Fab heavy chain, HSW-2 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZD
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BU of 7uzd by Molmil
Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, HSW-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-2 Fab heavy chain, HSW-2 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZC
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BU of 7uzc by Molmil
Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34
Descriptor: M8a-34 Fab heavy chain, M8a-34 Fab light chain, Spike protein S1, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
1OW0
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BU of 1ow0 by Molmil
Crystal structure of human FcaRI bound to IgA1-Fc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig alpha-1 chain C region, Immunoglobulin alpha Fc receptor, ...
Authors:Herr, A.B, Ballister, E.R, Bjorkman, P.J.
Deposit date:2003-03-27
Release date:2003-05-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc
Nature, 423, 2003
7LSE
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BU of 7lse by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Far Eastern Subtype)
Descriptor: Envelope protein E, GLYCEROL, T025 Fab Heavy Chain, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LSF
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BU of 7lsf by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype)
Descriptor: Envelope protein E, GLYCEROL, SODIUM ION, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LSG
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BU of 7lsg by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Siberian Subtype)
Descriptor: Core protein, T025 Fab Heavy Chain, T025 Fab Light Chain
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
5THR
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BU of 5thr by Molmil
Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex
Descriptor: 17b Fab VH domain, 17b Fab VL domain, 8ANC195 G52K5 VH domain, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2016-09-30
Release date:2016-11-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T3Z
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BU of 5t3z by Molmil
3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074
Descriptor: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gristick, H.B, Bjorkman, P.J.
Deposit date:2016-08-26
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
Nat.Struct.Mol.Biol., 23, 2016
3S3Y
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BU of 3s3y by Molmil
Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L0
Descriptor: SODIUM ION, TANDEM CYANOVIRIN-N DIMER CVN2L0
Authors:Keeffe, J.R, Bjorkman, P.J, Mayo, S.L.
Deposit date:2011-05-18
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
7K8T
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BU of 7k8t by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
Authors:Malyutin, A.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8X
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BU of 7k8x by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8S
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BU of 7k8s by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
Authors:Barnes, C.O, Malyutin, A.G, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
3S3Z
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BU of 3s3z by Molmil
Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L10
Descriptor: SODIUM ION, Tandem Cyanovirin-N Dimer CVN2L10
Authors:Keeffe, J.R, Bjorkman, P.J, Mayo, S.L.
Deposit date:2011-05-18
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
7KDE
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BU of 7kde by Molmil
BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-08
Release date:2020-10-28
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Elife, 9, 2020
5CAY
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BU of 5cay by Molmil
Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 core from ST strain of HIV-2, ...
Authors:Davenport, Y.W, Bjorkman, P.J.
Deposit date:2015-06-30
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
5UD9
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BU of 5ud9 by Molmil
Crystal structure of 354BG18 Fab
Descriptor: Fab heavy chain, Light chain
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2016-12-23
Release date:2017-02-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017

222415

数据于2024-07-10公开中

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