7UZB

Structure of the SARS-CoV-2 S S1 doamin in complex with the mouse antibody Fab fragment, HSW-2

Summary for 7UZB

Entry DOI	10.2210/pdb7uzb/pdb
EMDB information	26885
Descriptor	Spike glycoprotein, HSW-2 Fab heavy chain, HSW-2 Fab light chain, ... (4 entities in total)
Functional Keywords	immune system, neutralizing antibody, immune system-viral protein complex, immune system/viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	188541.04
Authors	Fan, C.,Bjorkman, P.J. (deposition date: 2022-05-08, release date: 2022-12-07, Last modification date: 2022-12-28)
Primary citation	Fan, C.,Cohen, A.A.,Park, M.,Hung, A.F.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Gao, H.,Kakutani, L.M.,Wu, Z.,Kleanthous, H.,Malecek, K.E.,Williams, J.C.,Bjorkman, P.J. Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes. Immunity, 55:2419-, 2022 Cited by PubMed: 36370711 DOI: 10.1016/j.immuni.2022.10.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation