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PDB: 202 件
5D4Q
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Crystal structure of GASDALIE IgG1 Fc
分子名称: Ig gamma-1 chain C region, alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ahmed, A.A, Bjorkman, P.J.
登録日2015-08-08
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
1T7X
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Zn-alpha-2-glycoprotein; refolded CHO-ZAG PEG 400
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Zinc-alpha-2-glycoprotein
著者Delker, S.L, West Jr, A.P, McDermott, L, Kennedy, M.W, Bjorkman, P.J.
登録日2004-05-11
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.
J.Struct.Biol., 148, 2004
1T7W
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Zn-alpha-2-glycoprotein; CHO-ZAG PEG 400
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Zinc-alpha-2-glycoprotein
著者Delker, S.L, West Jr, A.P, McDermott, L, Kennedy, M.W, Bjorkman, P.J.
登録日2004-05-11
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.
J.Struct.Biol., 148, 2004
2GIY
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Crystal Structure of the C-terminal domain of the HSV-1 gE ectodomain
分子名称: Glycoprotein E
著者Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
登録日2006-03-29
公開日2006-05-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
1T7Y
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Zn-alpha-2-glycoprotein; baculo-ZAG PEG 200, no glycerol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Zinc-alpha-2-glycoprotein
著者Delker, S.L, West Jr, A.P, McDermott, L, Kennedy, M.W, Bjorkman, P.J.
登録日2004-05-11
公開日2004-12-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.
J.Struct.Biol., 148, 2004
1T7Z
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Zn-alpha-2-glycoprotein; baculo-ZAG no PEG, no glycerol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Zinc-alpha-2-glycoprotein
著者Delker, S.L, West Jr, A.P, McDermott, L, Kennedy, M.W, Bjorkman, P.J.
登録日2004-05-11
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.
J.Struct.Biol., 148, 2004
2GJ7
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Crystal Structure of a gE-gI/Fc complex
分子名称: Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
登録日2006-03-30
公開日2006-05-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
6MEF
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Crystal structure of broadly neutralizing antibody AR3C
分子名称: antibody AR3C Heavy Chain, antibody AR3C Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2018-09-06
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
1FRT
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CRYSTAL STRUCTURE OF THE COMPLEX OF RAT NEONATAL FC RECEPTOR WITH FC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA 2-MICROGLOBULIN, IGG FC, ...
著者Burmeister, W.P, Bjorkman, P.J.
登録日1994-11-11
公開日1995-02-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Crystal structure of the complex of rat neonatal Fc receptor with Fc.
Nature, 372, 1994
7KL9
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Structure of the SARS-CoV-2 S 6P trimer in complex with the ACE2 protein decoy, CTC-445.2 (State 4)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CTC-445.2 inhibitor, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2020-10-29
公開日2020-11-11
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Science, 370, 2020
1G0X
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2)
分子名称: LEUCOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR-1
著者Chapman, T.L, Heikema, A.P, West Jr, A.P, Bjorkman, P.J.
登録日2000-10-09
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2).
Immunity, 13, 2000
1Z8L
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Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Davis, M.I, Bennett, M.J, Thomas, L.M, Bjorkman, P.J.
登録日2005-03-30
公開日2005-04-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase
Proc.Natl.Acad.Sci.USA, 102, 2005
1EXU
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CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR
分子名称: BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, IGG RECEPTOR FCRN LARGE SUBUNIT P51
著者West Jr, A.P, Bjorkman, P.J.
登録日2000-05-04
公開日2000-08-10
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,).
Biochemistry, 39, 2000
7RYU
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Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
分子名称: Ab1303 Fab heavy chain, Ab1303 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7LOK
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Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
分子名称: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jette, C.A, Bjorkman, P.J.
登録日2021-02-10
公開日2021-04-14
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Nat Commun, 12, 2021
7LO6
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Structure of CD4 mimetic BNM-III-170 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
分子名称: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jette, C.A, Bjorkman, P.J.
登録日2021-02-09
公開日2021-04-14
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Nat Commun, 12, 2021
4Q6Y
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Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-23
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4Q74
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F241A Fc
分子名称: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-24
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4Q7D
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Wild type Fc (wtFc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-24
公開日2014-07-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
1W9R
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Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
分子名称: CHOLINE BINDING PROTEIN A
著者Luo, R, Mann, B, Lewis, W.S, Rowe, A, Heath, R, Stewart, M.L, Hamburger, A.E, Bjorkman, P.J, Sivakolundu, S, Lacy, E.R, Tuomanen, E, Kriwacki, R.W.
登録日2004-10-15
公開日2005-02-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of Choline Binding Protein A, the Major Adhesin of Streptococcus Pneumoniae
Embo J., 24, 2005
1ZS8
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Crystal Structure of the Murine MHC Class Ib Molecule M10.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, histocompatibility 2, ...
著者Olson, R, Huey-Tubman, K.E, Dulac, C, Bjorkman, P.J.
登録日2005-07-22
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a pheromone receptor-associated MHC molecule with an open and empty groove.
Plos Biol., 3, 2005
1DE4
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HEMOCHROMATOSIS PROTEIN HFE COMPLEXED WITH TRANSFERRIN RECEPTOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2-MICROGLOBULIN, CALCIUM ION, ...
著者Bennett, M.J, Lebron, J.A, Bjorkman, P.J.
登録日1999-11-12
公開日2000-01-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor.
Nature, 403, 2000
1CFB
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CRYSTAL STRUCTURE OF TANDEM TYPE III FIBRONECTIN DOMAINS FROM DROSOPHILA NEUROGLIAN AT 2.0 ANGSTROMS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DROSOPHILA NEUROGLIAN, ...
著者Huber, A.H, Wang, Y.E, Bieber, A.J, Bjorkman, P.J.
登録日1994-08-27
公開日1994-11-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of tandem type III fibronectin domains from Drosophila neuroglian at 2.0 A.
Neuron, 12, 1994
1DQO
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Crystal structure of the cysteine rich domain of mannose receptor complexed with Acetylgalactosamine-4-sulfate
分子名称: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, MANNOSE RECEPTOR
著者Liu, Y, Chirino, A.J, Misulovin, Z, Leteux, C, Feizi, T, Nussenzweig, M.C, Bjorkman, P.J.
登録日2000-01-04
公開日2000-05-10
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand.
J.Exp.Med., 191, 2000
1FWV
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH 3-SO4-LEWIS(A)
分子名称: 3-O-sulfo-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR
著者Liu, Y, Misulovin, Z, Bjorkman, P.J.
登録日2000-09-24
公開日2001-01-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The molecular mechanism of sulfated carbohydrate recognition by the cysteine-rich domain of mannose receptor.
J.Mol.Biol., 305, 2001

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