5LKY
| X-ray crystal structure of N-acetylneuraminic acid lyase in complex with pyruvate, with the phenylalanine at position 190 replaced with the non-canonical amino acid dihydroxypropylcysteine. | 分子名称: | DI(HYDROXYETHYL)ETHER, N-acetylneuraminate lyase | 著者 | Windle, C.L, Trinh, C.H, Pearson, A.R, Nelson, A.S, Berry, A. | 登録日 | 2016-07-25 | 公開日 | 2017-03-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Extending enzyme molecular recognition with an expanded amino acid alphabet. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2WO5
| Structure of wild type E. coli N-acetylneuraminic acid lyase in space group P21 crystal form I | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-07-21 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
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2WNQ
| Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in space group P21 | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-07-17 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
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4AMA
| Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A. | 登録日 | 2012-03-08 | 公開日 | 2013-01-23 | 最終更新日 | 2019-07-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with gamma-thialysine by using a chemical mutagenesis strategy. Chembiochem, 14, 2013
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4BWL
| Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid | 分子名称: | 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, N-ACETYLNEURAMINATE LYASE, ... | 著者 | Campeotto, I, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2013-07-03 | 公開日 | 2014-02-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, Qm/Mm Simulation and Mutagenesis. Acs Chem.Biol., 9, 2014
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5A8G
| Crystal structure of the wild-type Staphylococcus aureus N- acetylneurminic acid lyase in complex with fluoropyruvate | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Stockwell, J, Daniels, A.D, Windle, C.L, Harman, T, Woodhall, T, Trinh, C.H, Lebel, T, Pearson, A.R, Mulholland, K, Berry, A, Nelson, A. | 登録日 | 2015-07-15 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Evaluation of Fluoropyruvate as Nucleophile in Reactions Catalysed by N-Acetyl Neuraminic Acid Lyase Variants: Scope, Limitations and Stereoselectivity. Org.Biomol.Chem., 14, 2016
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6HNM
| Crystal structure of IdmH 96-104 loop truncation variant | 分子名称: | putative polyketide cyclase IdmH | 著者 | Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A. | 登録日 | 2018-09-16 | 公開日 | 2019-11-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. Iucrj, 6, 2019
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6HNN
| Crystal structure of wild-type IdmH, a putative polyketide cyclase from Streptomyces antibioticus | 分子名称: | Putative polyketide cyclase IdmH | 著者 | Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A. | 登録日 | 2018-09-16 | 公開日 | 2019-11-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. Iucrj, 6, 2019
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6HNL
| Selenomethionine derivative of IdmH 96-104 loop truncation variant | 分子名称: | Putative polyketide cyclase IdmH | 著者 | Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A. | 登録日 | 2018-09-16 | 公開日 | 2019-11-06 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. Iucrj, 6, 2019
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4AH7
| Structure of Wild Type Stapylococcus aureus N-acetylneuraminic acid lyase in complex with pyruvate | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Poyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A. | 登録日 | 2012-02-03 | 公開日 | 2013-01-23 | 最終更新日 | 2013-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14, 2013
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4AHQ
| Crystal Structure of N-acetylneuraminic acid lyase mutant K165C from Staphylococcus aureus | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | 登録日 | 2012-02-06 | 公開日 | 2013-01-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14, 2013
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4AHO
| Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | 登録日 | 2012-02-06 | 公開日 | 2013-01-23 | 最終更新日 | 2013-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14, 2013
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4AHP
| Crystal Structure of Wild Type N-acetylneuraminic acid lyase from Staphylococcus aureus | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | 登録日 | 2012-02-06 | 公開日 | 2013-01-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14, 2013
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2WNZ
| Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 crystal form I | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, 2-ETHOXYETHANOL, LACTIC ACID, ... | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-07-21 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
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2WNN
| Structure of wild type E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 | 分子名称: | N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, SODIUM ION | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-07-13 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
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2WPB
| Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2R,3R)-2,3,4- trihydroxy-N,N-dipropylbutanamide in space group P21 crystal form I | 分子名称: | (2R,3R)-2,3,4-TRIHYDROXY-N,N-DIPROPYLBUTANAMIDE, N-ACETYLNEURAMINATE LYASE | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-08-03 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
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2XFW
| Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III | 分子名称: | N-ACETYLNEURAMINIC ACID LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | 著者 | Campeotto, I, Murshudov, G.N, Bolt, A.H, Trinh, C.H, Phillips, S.E.V, Nelson, A, Pearson, A.R, Berry, A. | 登録日 | 2010-05-28 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. To be Published
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1GYN
| Class II fructose 1,6-bisphosphate aldolase with Cadmium (not Zinc) in the active site | 分子名称: | CADMIUM ION, FRUCTOSE-BISPHOSPHATE ALDOLASE II | 著者 | Hall, D.R, Kemp, L.E, Leonard, G.A, Berry, A, Hunter, W.N. | 登録日 | 2002-04-27 | 公開日 | 2003-02-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase Acta Crystallogr.,Sect.D, 59, 2003
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2WKJ
| Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate at 1.45A resolution in space group P212121 | 分子名称: | N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | 著者 | Campeotto, I, Carr, S.B, Trinh, C.H, Nelson, A.S, Berry, A, Phillips, S.E.V, Pearson, A.R. | 登録日 | 2009-06-11 | 公開日 | 2009-12-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 65, 2009
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2YGY
| Structure of wild type E. coli N-acetylneuraminic acid lyase in space group P21 crystal form II | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL | 著者 | Campeotto, I, Nelson, A, Berry, A, Phillips, S.E.V, Pearson, A.R. | 登録日 | 2011-04-23 | 公開日 | 2012-04-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Pathological macromolecular crystallographic data affected by twinning, partial-disorder and exhibiting multiple lattices for testing of data processing and refinement tools. Sci Rep, 8, 2018
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