2XFW

Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III

Summary for 2XFW

• Entry DOI: 10.2210/pdb2xfw/pdb
• Descriptor: N-ACETYLNEURAMINIC ACID LYASE, PYRUVIC ACID, PENTAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: lyase
• Biological source: ESCHERICHIA COLI
• Cellular location: Cytoplasm (By similarity): B7M0T7
• Total number of polymer chains: 4
• Total formula weight: 136035.06

Authors

Campeotto, I.,Murshudov, G.N.,Bolt, A.H.,Trinh, C.H.,Phillips, S.E.V.,Nelson, A.,Pearson, A.R.,Berry, A. (deposition date: 2010-05-28, release date: 2010-09-22, Last modification date: 2023-12-20)

• Primary citation: Campeotto, I.,Bolt, A.H.,Harman, T.A.,Dennis, C.,Trinh, C.H.,Phillips, S.E.V.,Nelson, A.,Pearson, A.R.,Berry, A.; Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)