4AHO
Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165
Summary for 4AHO
| Entry DOI | 10.2210/pdb4aho/pdb |
| Related | 4AH7 4AHP 4AHQ |
| Descriptor | N-ACETYLNEURAMINATE LYASE, CHLORIDE ION (3 entities in total) |
| Functional Keywords | lyase |
| Biological source | STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325 |
| Cellular location | Cytoplasm (By similarity): Q2G160 |
| Total number of polymer chains | 4 |
| Total formula weight | 135831.30 |
| Authors | Timms, N.,Polyakova, A.,Windle, C.L.,Trinh, C.H.,Nelson, A.,Trinh, A.R.,Berry, A. (deposition date: 2012-02-06, release date: 2013-01-23, Last modification date: 2013-03-13) |
| Primary citation | Timms, N.,Windle, C.L.,Polyakova, A.,Ault, J.R.,Trinh, C.H.,Pearson, A.R.,Nelson, A.,Berry, A. Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14:474-, 2013 Cited by PubMed: 23418011DOI: 10.1002/CBIC.201200714 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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