5A8G

Crystal structure of the wild-type Staphylococcus aureus N- acetylneurminic acid lyase in complex with fluoropyruvate

Summary for 5A8G

Entry DOI	10.2210/pdb5a8g/pdb
Descriptor	N-ACETYLNEURAMINATE LYASE (2 entities in total)
Functional Keywords	lyase
Biological source	STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325
Cellular location	Cytoplasm : Q2G160
Total number of polymer chains	2
Total formula weight	68242.97
Authors	Stockwell, J.,Daniels, A.D.,Windle, C.L.,Harman, T.,Woodhall, T.,Trinh, C.H.,Lebel, T.,Pearson, A.R.,Mulholland, K.,Berry, A.,Nelson, A. (deposition date: 2015-07-15, release date: 2015-11-18, Last modification date: 2024-01-10)
Primary citation	Stockwell, J.,Daniels, A.D.,Windle, C.L.,Harman, T.A.,Woodhall, T.,Lebl, T.,Trinh, C.H.,Mulholland, K.,Pearson, A.R.,Berry, A.,Nelson, A. Evaluation of Fluoropyruvate as Nucleophile in Reactions Catalysed by N-Acetyl Neuraminic Acid Lyase Variants: Scope, Limitations and Stereoselectivity. Org.Biomol.Chem., 14:105-, 2016 Cited by PubMed: 26537532 DOI: 10.1039/C5OB02037A PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation