1ERB
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3DJS
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3DJZ
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5AL8
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![BU of 5al8 by Molmil](/molmil-images/mine/5al8) | Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: daidzein-7-O- glucuronide | Descriptor: | DAIDZEIN-7-O-GLUCURONIDE, TRANSTHYRETIN | Authors: | Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-06 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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5AKS
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![BU of 5aks by Molmil](/molmil-images/mine/5aks) | Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-3-O- glucuronide | Descriptor: | DIMETHYL SULFOXIDE, Resveratrol-3-O-glucuronide, SULFATE ION, ... | Authors: | Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-05 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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3Q1E
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![BU of 3q1e by Molmil](/molmil-images/mine/3q1e) | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | Deposit date: | 2010-12-17 | Release date: | 2011-05-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
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2G4G
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2G4E
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2G3Z
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2H6U
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![BU of 2h6u by Molmil](/molmil-images/mine/2h6u) | Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein) | Descriptor: | 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | Deposit date: | 2006-06-01 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter. J.Mol.Biol., 363, 2006
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2H1X
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![BU of 2h1x by Molmil](/molmil-images/mine/2h1x) | Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | Descriptor: | 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | Deposit date: | 2006-05-17 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter. J.Mol.Biol., 363, 2006
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4ALO
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![BU of 4alo by Molmil](/molmil-images/mine/4alo) | STRUCTURE AND PROPERTIES OF H1 CRUSTACYANIN FROM LOBSTER HOMARUS AMERICANUS | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, H1 APOCRUSTACYANIN, SODIUM ION, ... | Authors: | Ferrari, M, Folli, C, Pincolini, E, Mcclintock, T.S, Roessle, M, Berni, R, Cianci, M. | Deposit date: | 2012-03-05 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural Characterization of Recombinant Crustacyanin Subunits from the Lobster Homarus Americanus. Acta Crystallogr.,Sect.F, 68, 2012
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6R67
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![BU of 6r67 by Molmil](/molmil-images/mine/6r67) | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | Descriptor: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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6R68
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![BU of 6r68 by Molmil](/molmil-images/mine/6r68) | Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue | Descriptor: | (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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6R6I
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![BU of 6r6i by Molmil](/molmil-images/mine/6r6i) | Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-27 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.467 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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2G3X
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6R66
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![BU of 6r66 by Molmil](/molmil-images/mine/6r66) | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | Descriptor: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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1FEM
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![BU of 1fem by Molmil](/molmil-images/mine/1fem) | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | Descriptor: | RETINOIC ACID, RETINOL BINDING PROTEIN | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | Deposit date: | 1994-08-29 | Release date: | 1994-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein. J.Biol.Chem., 269, 1994
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1FEN
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![BU of 1fen by Molmil](/molmil-images/mine/1fen) | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | Descriptor: | ALL-TRANS AXEROPHTHENE, RETINOL BINDING PROTEIN | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | Deposit date: | 1994-08-29 | Release date: | 1994-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein. J.Biol.Chem., 269, 1994
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1FEL
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![BU of 1fel by Molmil](/molmil-images/mine/1fel) | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | Descriptor: | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE, RETINOL BINDING PROTEIN | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | Deposit date: | 1994-08-29 | Release date: | 1994-11-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein. J.Biol.Chem., 269, 1994
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1TYR
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![BU of 1tyr by Molmil](/molmil-images/mine/1tyr) | TRANSTHYRETIN COMPLEX WITH RETINOIC ACID | Descriptor: | (9cis)-retinoic acid, TRANSTHYRETIN | Authors: | Zanotti, G, D'Acunto, M.R, Malpeli, G, Folli, C, Berni, R. | Deposit date: | 1995-05-12 | Release date: | 1995-09-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the transthyretin--retinoic-acid complex Eur.J.Biochem., 234, 1995
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4I87
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![BU of 4i87 by Molmil](/molmil-images/mine/4i87) | Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | Deposit date: | 2012-12-03 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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4I85
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![BU of 4i85 by Molmil](/molmil-images/mine/4i85) | Crystal structure of transthyretin in complex with CHF5074 at neutral pH | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | Deposit date: | 2012-12-03 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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4I89
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![BU of 4i89 by Molmil](/molmil-images/mine/4i89) | Crystal structure of transthyretin in complex with diflunisal at acidic pH | Descriptor: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | Deposit date: | 2012-12-03 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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2B5S
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![BU of 2b5s by Molmil](/molmil-images/mine/2b5s) | Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens | Descriptor: | HEPTANE, LAURIC ACID, Non-specific lipid transfer protein, ... | Authors: | Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, R.J, Zanotti, G. | Deposit date: | 2005-09-29 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens J.Mol.Biol., 356, 2006
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