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PDB: 15 件
8DE6
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BU of 8de6 by Molmil
Oligomeric C9 in complex with aE11 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ...
著者Bayly-Jones, C.
登録日2022-06-20
公開日2023-01-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.
Commun Biol, 6, 2023
7UAI
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BU of 7uai by Molmil
Meprin alpha helix in complex with fetuin-B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日2022-03-13
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAF
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Human meprin alpha inhibitory complex with compound 10d (N~3~,N~3~-bis[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-beta-alaninamide)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日2022-03-12
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAB
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BU of 7uab by Molmil
Human pro-meprin alpha (zymogen state)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日2022-03-12
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAC
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BU of 7uac by Molmil
Human pro-meprin alpha (zymogen state)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Meprin A subunit alpha, ...
著者Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日2022-03-12
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAE
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BU of 7uae by Molmil
Human meprin alpha (active state)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日2022-03-12
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7MP5
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BU of 7mp5 by Molmil
Autoinhibited neurofibrobmin
分子名称: Isoform I of Neurofibromin
著者Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日2021-05-04
公開日2021-12-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MP6
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Neurofibromin homodimer
分子名称: Isoform I of Neurofibromin
著者Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日2021-05-04
公開日2021-12-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6.25 Å)
主引用文献The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MOC
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BU of 7moc by Molmil
Neurofibromin core
分子名称: Isoform I of Neurofibromin
著者Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日2021-05-01
公開日2021-12-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.56 Å)
主引用文献The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
6U2J
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BU of 6u2j by Molmil
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Pang, S.S, Bayly-Jones, C.
登録日2019-08-20
公開日2019-09-25
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.37 Å)
主引用文献The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2W
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BU of 6u2w by Molmil
EM structure of MPEG-1(L425K) pre-pore complex bound to liposome
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Pang, S.S, Bayly-Jones, C.
登録日2019-08-20
公開日2019-09-25
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
7SYF
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BU of 7syf by Molmil
Reconstruction of full-length Prex-1 (PtdIns(3,4,5)P3-dependent Rac Exchanger 1)
分子名称: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Endolysin chimera
著者Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日2021-11-24
公開日2022-07-27
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.
Nat.Struct.Mol.Biol., 29, 2022
6U23
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BU of 6u23 by Molmil
EM structure of MPEG-1(w.t.) soluble pre-pore
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Pang, S.S, Bayly-Jones, C.
登録日2019-08-19
公開日2019-09-25
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2L
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BU of 6u2l by Molmil
EM structure of MPEG-1 (L425K, beta conformation) soluble pre-pore complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Pang, S.S, Bayly-Jones, C.
登録日2019-08-20
公開日2019-09-25
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2K
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BU of 6u2k by Molmil
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Pang, S.S, Bayly-Jones, C.
登録日2019-08-20
公開日2019-09-25
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019

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件を2024-07-17に公開中

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