4FVV
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![BU of 4fvv by Molmil](/molmil-images/mine/4fvv) | Crystal structure of HCR/D-Sa-GBL1/C | Descriptor: | GLYCEROL, N-acetyl-alpha-neuraminic acid, Neurotoxin, ... | Authors: | Fu, Z, Karalewitz, A, Baldwin, M.R, Kim, J.-J.P, Barbieri, J.T. | Deposit date: | 2012-06-29 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry. J.Biol.Chem., 287, 2012
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4IQP
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![BU of 4iqp by Molmil](/molmil-images/mine/4iqp) | Crystal Structure of HCRA-W1266A | Descriptor: | Botulinum neurotoxin type A, GLYCEROL | Authors: | Fu, Z, Kroken, A.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2013-01-12 | Release date: | 2013-05-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enhancing the Protective Immune Response against Botulism. Infect.Immun., 81, 2013
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3FUQ
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![BU of 3fuq by Molmil](/molmil-images/mine/3fuq) | Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F | Descriptor: | BoNT/F (Neurotoxin type F) | Authors: | Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | Deposit date: | 2009-01-14 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F Biochemistry, 48, 2009
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3FUO
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![BU of 3fuo by Molmil](/molmil-images/mine/3fuo) | The Crystal structure of receptor binding domain of botulinum neurotoxin serotype A | Descriptor: | Botulinum neurotoxin type A | Authors: | Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | Deposit date: | 2009-01-14 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F Biochemistry, 48, 2009
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3HN1
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![BU of 3hn1 by Molmil](/molmil-images/mine/3hn1) | Crystal structure of HCR/T complexed with GT2 and lactose | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, SULFATE ION, Tetanus toxin, ... | Authors: | Chen, C, Fu, Z, Kim, J.-J.P, Barbieri, J.T, Baldwin, M.R. | Deposit date: | 2009-05-29 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Gangliosides as high affinity receptors for tetanus neurotoxin. J.Biol.Chem., 284, 2009
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1HE1
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![BU of 1he1 by Molmil](/molmil-images/mine/1he1) | Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac | Descriptor: | ALUMINUM FLUORIDE, EXOENZYME S, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Wurtele, M, Wolf, E, Pederson, K.J, Buchwald, G, Ahmadian, M.R, Barbieri, J.T, Wittinghofer, A. | Deposit date: | 2000-11-18 | Release date: | 2001-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How the Pseudomonas Aeruginosa Exos Toxin Downregulates Rac Nat.Struct.Biol., 8, 2001
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1HE9
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![BU of 1he9 by Molmil](/molmil-images/mine/1he9) | Crystal structure of the GAP domain of the Pseudomonas aeruginosa ExoS toxin | Descriptor: | EXOENZYME S | Authors: | Wurtele, M, Renault, L, Barbieri, J.T, Wittinghofer, A, Wolf, E. | Deposit date: | 2000-11-21 | Release date: | 2001-03-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the Exos Gtpase Activating Domain FEBS Lett., 491, 2001
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3HMY
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![BU of 3hmy by Molmil](/molmil-images/mine/3hmy) | Crystal structure of HCR/T complexed with GT2 | Descriptor: | GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, SULFATE ION, ... | Authors: | Chen, C, Fu, Z, Kim, J.-J.P, Barbieri, J.T, Baldwin, M.R. | Deposit date: | 2009-05-29 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Gangliosides as high affinity receptors for tetanus neurotoxin. J.Biol.Chem., 284, 2009
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2G7P
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![BU of 2g7p by Molmil](/molmil-images/mine/2g7p) | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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2G7N
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![BU of 2g7n by Molmil](/molmil-images/mine/2g7n) | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, SILVER ION, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors To be Published
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2G7K
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![BU of 2g7k by Molmil](/molmil-images/mine/2g7k) | Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Crawford, A, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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2G7Q
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![BU of 2g7q by Molmil](/molmil-images/mine/2g7q) | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, N-HYDROXY-L-ARGININAMIDE, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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3RMY
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![BU of 3rmy by Molmil](/molmil-images/mine/3rmy) | Crystal structure of HCR/D W1238A mutant | Descriptor: | Botulinum neurotoxin type D, GLYCEROL | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Kim, J.-J.P, Barbieri, J.T. | Deposit date: | 2011-04-21 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons. J.Biol.Chem., 286, 2011
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3RMX
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![BU of 3rmx by Molmil](/molmil-images/mine/3rmx) | Crystal structure of HCR/D F1240A mutant | Descriptor: | Botulinum neurotoxin type D | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Kim, J.-J.P, Barbieri, J.T. | Deposit date: | 2011-04-21 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons. J.Biol.Chem., 286, 2011
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3N7M
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![BU of 3n7m by Molmil](/molmil-images/mine/3n7m) | Crystal structure of W1252A mutant of HCR D/C VPI 5995 | Descriptor: | GLYCEROL, Neurotoxin, SULFATE ION | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3N7K
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![BU of 3n7k by Molmil](/molmil-images/mine/3n7k) | Crystal structure of botulinum neurotoxin serotype C1 binding domain | Descriptor: | Botulinum neurotoxin type C1 | Authors: | Fu, Z, Kroken, A, Karalewitz, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3N7J
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![BU of 3n7j by Molmil](/molmil-images/mine/3n7j) | Crystal structure of botulinum neurotoxin serotype D binding domain | Descriptor: | Botulinum neurotoxin type D | Authors: | Fu, Z, Baldwin, M.R, Karalewitz, A, Kroken, A, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3N7L
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![BU of 3n7l by Molmil](/molmil-images/mine/3n7l) | Crystal structure of botulinum neurotoxin serotype D/C VPI 5993 binding domain | Descriptor: | GLYCEROL, Neurotoxin, SULFATE ION | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3RSJ
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![BU of 3rsj by Molmil](/molmil-images/mine/3rsj) | Structure of HCRF in complex with Ganglioside GD1a | Descriptor: | BoNT/F, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, ... | Authors: | Fu, Z, Benson, M.A, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | Deposit date: | 2011-05-02 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Unique ganglioside recognition strategies for clostridial neurotoxins. J.Biol.Chem., 286, 2011
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