3N7M

Crystal structure of W1252A mutant of HCR D/C VPI 5995

Summary for 3N7M

• Entry DOI: 10.2210/pdb3n7m/pdb
• Related: 3N7J 3N7K 3N7L
• Descriptor: Neurotoxin, SULFATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: botulinum neurotoxin, w1252a mutant, gm1a, ganglioside binding loop, toxin
• Biological source: Clostridium botulinum
• Total number of polymer chains: 1
• Total formula weight: 49111.20

Authors

Fu, Z.,Karalewitz, A.,Kroken, A.,Baldwin, M.R.,Barbieri, J.T.,Kim, J.-J.P. (deposition date: 2010-05-27, release date: 2010-09-08, Last modification date: 2023-09-06)

• Primary citation: Karalewitz, A.P.,Kroken, A.R.,Fu, Z.,Baldwin, M.R.,Kim, J.J.,Barbieri, J.T.; Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .; Biochemistry, 49:8117-8126, 2010; PubMed: 20731382; DOI: 10.1021/bi100865f

Experimental method

X-RAY DIFFRACTION (2.6 Å)