3N7J

Crystal structure of botulinum neurotoxin serotype D binding domain

Summary for 3N7J

• Entry DOI: 10.2210/pdb3n7j/pdb
• Related: 3N7K 3N7L 3N7M
• Descriptor: Botulinum neurotoxin type D (2 entities in total)
• Functional Keywords: botulinum neurotoxin, hcr/d, ganglioside binding loop, toxin
• Biological source: Clostridium botulinum
• Cellular location: Botulinum neurotoxin D light chain: Secreted. Botulinum neurotoxin D heavy chain: Secreted: P19321
• Total number of polymer chains: 1
• Total formula weight: 48237.25

Authors

Fu, Z.,Baldwin, M.R.,Karalewitz, A.,Kroken, A.,Barbieri, J.T.,Kim, J.-J.P. (deposition date: 2010-05-27, release date: 2010-09-08, Last modification date: 2023-09-06)

• Primary citation: Karalewitz, A.P.,Kroken, A.R.,Fu, Z.,Baldwin, M.R.,Kim, J.J.,Barbieri, J.T.; Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .; Biochemistry, 49:8117-8126, 2010; PubMed: 20731382; DOI: 10.1021/bi100865f

Experimental method

X-RAY DIFFRACTION (2 Å)