Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 3979 results

4UUU
DownloadVisualize
BU of 4uuu by Molmil
1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM
Descriptor: 1,2-ETHANEDIOL, CYSTATHIONINE BETA-SYNTHASE, S-ADENOSYLMETHIONINE
Authors:Kopec, J, McCorvie, T.J, Fitzpatrick, F, Strain-Damerell, C, Froese, D.S, Tallant, C, Burgess-Brown, N, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
Deposit date:2014-07-31
Release date:2014-08-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation.
J.Biol.Chem., 289, 2014
7A21
DownloadVisualize
BU of 7a21 by Molmil
Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2158
Descriptor: 1,2-ETHANEDIOL, 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type I, ...
Authors:Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2020-08-14
Release date:2020-09-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2153
To Be Published
6ZU8
DownloadVisualize
BU of 6zu8 by Molmil
Crystal structure of human Brachyury G177D variant in complex with Afatinib
Descriptor: Brachyury protein, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide, ZINC ION
Authors:Newman, J.A, Gavard, A.E, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2020-07-21
Release date:2020-08-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human Brachyury G177D variant in complex with Afatinib
To Be Published
6OOV
DownloadVisualize
BU of 6oov by Molmil
Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA
Descriptor: DNA (5'-D(*CP*AP*AP*CP*GP*TP*TP*GP*TP*TP*TP*TP*T)-3'), Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, UNKNOWN ATOM OR ION
Authors:Halabelian, L, Zeng, H, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2019-04-23
Release date:2019-05-15
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA
To Be Published
8BLU
DownloadVisualize
BU of 8blu by Molmil
The PDZ domains of human SDCBP
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALANINE, ...
Authors:Bradshaw, W.J, Katis, V.L, Daniel-Mozo, M, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2022-11-10
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The PDZ domains of human SDCBP
To Be Published
4UY4
DownloadVisualize
BU of 4uy4 by Molmil
1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide
Descriptor: GLYCEROL, HISTONE H3K4ME3, SPINDLIN-4
Authors:Talon, R, Gileadi, C, Johansson, C, Burgess-Brown, N, Shrestha, L, von Delft, F, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U.
Deposit date:2014-08-28
Release date:2014-09-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.862 Å)
Cite:1.86 A Structure of Human Spindlin-4 Protein in Complex with Histone H3K4Me3 Peptide
To be Published
4URJ
DownloadVisualize
BU of 4urj by Molmil
Crystal structure of human BJ-TSA-9
Descriptor: 1,2-ETHANEDIOL, PROTEIN FAM83A
Authors:Pinkas, D.M, Sanvitale, C, Wang, D, Krojer, T, Kopec, J, Chaikuad, A, Dixon Clarke, S, Berridge, G, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Bullock, A.
Deposit date:2014-06-30
Release date:2014-10-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Crystal Structure of Human Bj-Tsa-9
To be Published
8BNT
DownloadVisualize
BU of 8bnt by Molmil
The DH domain of ARHGEF2 bound to RhoA
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, Rho guanine nucleotide exchange factor 2, ...
Authors:Bradshaw, W.J, Katis, V.L, Grosjean, H, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2022-11-25
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The DH domain of ARHGEF2 bound to RhoA
To Be Published
8F0W
DownloadVisualize
BU of 8f0w by Molmil
Tudor Domain of Tumor suppressor p53BP1 with MFP-5956
Descriptor: 1-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]butan-1-one, TP53-binding protein 1, UNKNOWN ATOM OR ION
Authors:The, J, Hong, Z, Dong, A, Headey, S, Gunzburg, M, Doak, B, James, L.I, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2022-11-04
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Tudor Domain of Tumor suppressor p53BP1 with MFP-5956
to be published
8BLV
DownloadVisualize
BU of 8blv by Molmil
The PDZ domains of human SDCBP with a bound SDC4 C-terminal peptide
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Syndecan-4, ...
Authors:Bradshaw, W.J, Katis, V.L, Daniel-Mozo, M, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2022-11-10
Release date:2022-12-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The PDZ domains of human SDCBP with a bound SDC4 C-terminal peptide
To Be Published
8W3V
DownloadVisualize
BU of 8w3v by Molmil
Crystal structure of human WDR41
Descriptor: WD repeat-containing protein 41
Authors:Hutchinson, A, Dong, A, Li, Y, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
Deposit date:2024-02-22
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human WDR41
To be published
5JJX
DownloadVisualize
BU of 5jjx by Molmil
Crystal structure of the HAT domain of sart3
Descriptor: CHLORIDE ION, Squamous cell carcinoma antigen recognized by T-cells 3, UNKNOWN ATOM OR ION
Authors:DONG, A, ZHANG, Q, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC)
Deposit date:2016-04-25
Release date:2016-05-04
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the HAT domain of sart3
to be published
5JJZ
DownloadVisualize
BU of 5jjz by Molmil
Chromo domain of human Chromodomain Protein, Y-Like 2
Descriptor: Chromodomain Y-like protein 2, LYS-LYS-LYS-ALA-ARG-MLY-SER-ALA-GLY-ALA-ALA-LYS-TYR
Authors:DONG, A, DOMBROVSKI, L, LOPPNAU, P, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, MIN, J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2016-04-25
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of CDYL2 domain of human CDYL2 protein
to be published
5JMS
DownloadVisualize
BU of 5jms by Molmil
Crystal structure of TgCDPK1 bound to CGP060476
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Calmodulin-domain protein kinase 1, ...
Authors:El Bakkouri, M, Walker, J.R, Loppnau, P, Graslund, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Lovato, D.V, Structural Genomics Consortium (SGC)
Deposit date:2016-04-29
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of TgCDPK1bount to CGP060476
To Be Published
7R4N
DownloadVisualize
BU of 7r4n by Molmil
Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide
Descriptor: 1,2-ETHANEDIOL, 5-bromanyl-N-methyl-1H-indazole-3-carboxamide, FLAVIN MONONUCLEOTIDE, ...
Authors:Mackinnon, S, Bezerra, G.A, Krojer, T, Bradley, A.R, Talon, R, Brandeo-Neto, J, Douangamath, A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W.
Deposit date:2022-02-08
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide
To Be Published
7R51
DownloadVisualize
BU of 7r51 by Molmil
Structure of P. gingivalis DPP11 in complex with the dipeptide Arg-Asp
Descriptor: ARG-ASP, Asp/Glu-specific dipeptidyl-peptidase
Authors:Tham, C.T, Coker, J.A, Foster, W.R, Ohara-Nemoto, Y, Nemoto, T.K, Yue, W.W, Bountra, C, Bezerra, G.A.
Deposit date:2022-02-09
Release date:2022-05-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.808 Å)
Cite:Structure of P. gingivalis DPP11 in complex with the dipeptide Arg-Asp
To Be Published
7R4O
DownloadVisualize
BU of 7r4o by Molmil
Structure of human hydroxyacid oxidase 1 bound with 2-((4H-1,2,4-triazol-3-yl)thio)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one
Descriptor: 2-((4H-1,2,4-triazol-3-yl)thio)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1
Authors:Mackinnon, S, Bezerra, G.A, Krojer, T, Bradley, A.R, Talon, R, Brandeo-Neto, J, Douangamath, A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W.
Deposit date:2022-02-08
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide
To Be Published
7R4P
DownloadVisualize
BU of 7r4p by Molmil
Structure of human hydroxyacid oxidase 1 bound with 6-amino-1-benzyl-5-(methylamino)pyrimidine-2,4(1H,3H)-dione
Descriptor: 6-amino-1-benzyl-5-(methylamino)pyrimidine-2,4(1H,3H)-dione, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1
Authors:Mackinnon, S, Bezerra, G.A, Krojer, T, Bradley, A.R, Talon, R, Brandeo-Neto, J, Douangamath, A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Brennan, P.E, Yue, W.W.
Deposit date:2022-02-09
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide
To Be Published
5J3E
DownloadVisualize
BU of 5j3e by Molmil
Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA
Descriptor: 5-methylcytosine containing DNA, Thymocyte nuclear protein 1, UNKNOWN ATOM OR ION
Authors:Halabelian, L, Tempel, W, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2016-03-30
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA
To be published
6UPT
DownloadVisualize
BU of 6upt by Molmil
Tudor Domain of Tumor suppressor p53BP1 with MFP-2706
Descriptor: 2-((2-chlorobenzyl)thio)-4,5-dihydro-1H-imidazole, TP53-binding protein 1, UNKNOWN ATOM OR ION
Authors:The, J, Dong, A, Headey, S, Gunzburg, M, Doak, B, James, L.I, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2019-10-18
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Tudor Domain of Tumor suppressor p53BP1 with MFP-2706
to be published
6VAH
DownloadVisualize
BU of 6vah by Molmil
Crystal structure of human TEAD2 transcription factor in complex with Flufenamic acid derivative
Descriptor: 2-fluoro-6-[(3-hexylphenyl)amino]benzoic acid, Transcriptional enhancer factor TEF-4, UNKNOWN ATOM OR ION
Authors:Halabelian, L, Zeng, H, Dong, A, Li, Y, Melin, L, Gagnon, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Santhakumar, V, Structural Genomics Consortium (SGC)
Deposit date:2019-12-17
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of human TEAD2 transcription factor in complex with Flufenamic acid derivative
to be published
4E71
DownloadVisualize
BU of 4e71 by Molmil
Crystal structure of the RHO GTPASE binding domain of Plexin B2
Descriptor: Plexin-B2, SODIUM ION
Authors:Guan, X, Wang, H, Tempel, W, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2012-03-16
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of the RHO GTPASE binding domain of Plexin B2
to be published
4E74
DownloadVisualize
BU of 4e74 by Molmil
Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A
Descriptor: Plexin-A4, UNKNOWN ATOM OR ION
Authors:Guan, X, Wang, H, Tempel, W, Dong, A, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2012-03-16
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A
to be published
3C5K
DownloadVisualize
BU of 3c5k by Molmil
Crystal structure of human HDAC6 zinc finger domain
Descriptor: Histone deacetylase 6, ZINC ION
Authors:Dong, A, Ravichandran, M, Schuetz, A, Loppnau, P, Li, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Dhe-Paganon, S, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
Deposit date:2008-01-31
Release date:2008-02-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of Human HDAC6 zinc finger domain.
To be Published
3C5H
DownloadVisualize
BU of 3c5h by Molmil
Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP)
Descriptor: Glucocorticoid receptor DNA-binding factor 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-01-31
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP).
To be Published

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon