2EZ2
 
 | | Apo tyrosine phenol-lyase from Citrobacter freundii at pH 8.0 | | Descriptor: | PHOSPHATE ION, POTASSIUM ION, Tyrosine phenol-lyase | | Authors: | Milic, D, Matkovic-Calogovic, D, Demidkina, T.V, Antson, A.A. | | Deposit date: | 2005-11-10 | | Release date: | 2006-07-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions
Biochemistry, 45, 2006
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2JEX
 | | Transcription activator structure reveals redox control of a replication initiation reaction | | Descriptor: | REGULATORY PROTEIN E2 | | Authors: | Sanders, C.M, Sizov, D, Seavers, P.R, Ortiz-Lombardia, M, Antson, A.A. | | Deposit date: | 2007-01-24 | | Release date: | 2007-05-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Transcription Activator Structure Reveals Redox Control of a Replication Initiation Reaction.
Nucleic Acids Res., 35, 2007
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2JK3
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2FX0
 | | Crystal Structure of HlyIIR, a Hemolysin II transcriptional Regulator | | Descriptor: | hemolysin II regulatory protein | | Authors: | Kovalevskiy, O.V, Lebedev, A.A, Solonin, A.S, Antson, A.A. | | Deposit date: | 2006-02-03 | | Release date: | 2006-02-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Bacillus cereus HlyIIR, a Transcriptional Regulator of the Gene for Pore-forming Toxin Hemolysin II.
J.Mol.Biol., 365, 2007
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5MFX
 | | Zika NS3 helicase:RNA complex | | Descriptor: | ACETATE ION, CITRATE ANION, Genome polyprotein, ... | | Authors: | Jenkins, H.T, Ge, M, Chechik, M, Greive, S.J, Antson, A.A. | | Deposit date: | 2016-11-18 | | Release date: | 2017-01-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.598 Å) | | Cite: | How Zika virus NS3 helicase grips the first
nucleotide of the leading RNA strand
To Be Published
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2WBN
 | | Crystal structure of the g2p (large terminase) nuclease domain from the bacteriophage SPP1 | | Descriptor: | TERMINASE LARGE SUBUNIT | | Authors: | Smits, C, Chechik, M, Kovalevskiy, O.V, Shevtsov, M.B, Foster, A.W, Alonso, J.C, Antson, A.A. | | Deposit date: | 2009-03-02 | | Release date: | 2009-03-24 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for the Nuclease Activity of a Bacteriophage Large Terminase.
Embo Rep., 10, 2009
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2WNR
 | | The structure of Methanothermobacter thermautotrophicus exosome core assembly | | Descriptor: | PHOSPHATE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, PROBABLE EXOSOME COMPLEX EXONUCLEASE 2 | | Authors: | Ng, C.L, Waterman, D.G, Antson, A.A, Ortiz-Lombardia, M. | | Deposit date: | 2009-07-19 | | Release date: | 2010-04-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of the Methanothermobacter Thermautotrophicus Exosome Rnase Ph Ring
Acta Crystallogr.,Sect.D, 66, 2010
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2VLF
 | | Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with alanine | | Descriptor: | (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}PROPANOIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, POTASSIUM ION, ... | | Authors: | Milic, D, Demidkina, T.V, Matkovic-Calogovic, D, Antson, A.A. | | Deposit date: | 2008-01-14 | | Release date: | 2008-08-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Insights Into the Catalytic Mechanism of Tyrosine Phenol-Lyase from X-Ray Structures of Quinonoid Intermediates.
J.Biol.Chem., 283, 2008
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2V9P
 | | Crystal structure of papillomavirus E1 hexameric helicase DNA-free form | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1 | | Authors: | Sanders, C.M, Kovalevskiy, O.V, Sizov, D, Lebedev, A.A, Isupov, M.N, Antson, A.A. | | Deposit date: | 2007-08-24 | | Release date: | 2007-10-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Papillomavirus E1 Helicase Assembly Maintains an Asymmetric State in the Absence of DNA and Nucleotide Cofactors.
Nucleic Acids Res., 35, 2007
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2WC9
 | | Crystal structure of the g2p (large terminase) nuclease domain from the bacteriophage SPP1 with bound Mn | | Descriptor: | MANGANESE (II) ION, SULFATE ION, TERMINASE LARGE SUBUNIT | | Authors: | Smits, C, Chechik, M, Kovalevskiy, O.V, Shevtsov, M.B, Foster, A.W, Alonso, J.C, Antson, A.A. | | Deposit date: | 2009-03-10 | | Release date: | 2009-03-24 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for the Nuclease Activity of a Bacteriophage Large Terminase.
Embo Rep., 10, 2009
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2JES
 | | Portal protein (gp6) from bacteriophage SPP1 | | Descriptor: | CALCIUM ION, MERCURY (II) ION, PORTAL PROTEIN, ... | | Authors: | Lebedev, A.A, Krause, M.H, Isidro, A.L, Vagin, A.A, Orlova, E.V, Turner, J, Dodson, E.J, Tavares, P, Antson, A.A. | | Deposit date: | 2007-01-21 | | Release date: | 2007-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural Framework for DNA Translocation Via the Viral Portal Protein
Embo J., 26, 2007
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5M1Q
 | | Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Zinc | | Descriptor: | Phage terminase large subunit, ZINC ION | | Authors: | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | | Deposit date: | 2016-10-09 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
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5NGD
 | | Crystal structure of the V325G mutant of the bacteriophage G20C portal protein | | Descriptor: | Portal protein | | Authors: | Pascoa, T, Jenkins, H.T, Chechik, M, Greive, S.J, Antson, A.A. | | Deposit date: | 2017-03-17 | | Release date: | 2017-03-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Porphyrin-Assisted Docking of a Thermophage Portal Protein into Lipid Bilayers: Nanopore Engineering and Characterization
Acs Nano, 11, 2017
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5M1K
 | | Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Magnesium | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Phage terminase large subunit, ... | | Authors: | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | | Deposit date: | 2016-10-09 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
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5M1P
 | | Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Calcium | | Descriptor: | CALCIUM ION, Terminase large subunit | | Authors: | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | | Deposit date: | 2016-10-09 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
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5M1N
 | | Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Manganese | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, Phage terminase large subunit, ... | | Authors: | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | | Deposit date: | 2016-10-09 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
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2WBM
 | | Crystal structure of mthSBDS, the homologue of the Shwachman-Bodian- Diamond syndrome protein in the euriarchaeon Methanothermobacter thermautotrophicus | | Descriptor: | CHLORIDE ION, GLYCEROL, RIBOSOME MATURATION PROTEIN SDO1 HOMOLOG, ... | | Authors: | Ng, C.L, Isupov, M.N, Lebedev, A.A, Ortiz-Lombardia, M, Antson, A.A. | | Deposit date: | 2009-03-02 | | Release date: | 2009-06-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Conformational Flexibility and Molecular Interactions of an Archaeal Homologue of the Shwachman-Bodian-Diamond Syndrome Protein.
Bmc Struct.Biol., 9, 2009
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5OK9
 | | CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with swapped phosphopeptides | | Descriptor: | 14-3-3 protein sigma,Heat shock protein beta-6, DI(HYDROXYETHYL)ETHER | | Authors: | Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A. | | Deposit date: | 2017-07-25 | | Release date: | 2017-10-11 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners.
Sci Rep, 7, 2017
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2VLH
 | | Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with methionine | | Descriptor: | (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, POTASSIUM ION, ... | | Authors: | Milic, D, Demidkina, T.V, Matkovic-Calogovic, D, Antson, A.A. | | Deposit date: | 2008-01-14 | | Release date: | 2008-08-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Insights Into the Catalytic Mechanism of Tyrosine Phenol-Lyase from X-Ray Structures of Quinonoid Intermediates.
J.Biol.Chem., 283, 2008
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5LU1
 | | Human 14-3-3 sigma CLU3 mutant complexed with short HSPB6 phosphopeptide | | Descriptor: | 14-3-3 protein sigma, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heat shock protein beta-6 | | Authors: | Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V. | | Deposit date: | 2016-09-07 | | Release date: | 2017-02-01 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
Structure, 25, 2017
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5OE9
 | | Structure of large terminase from the thermophilic bacteriophage D6E in complex with sulfate (Crystal form 2) | | Descriptor: | Large subunit terminase, SULFATE ION | | Authors: | Xu, R.G, Jenkins, H.T, Greive, S.J, Antson, A.A. | | Deposit date: | 2017-07-07 | | Release date: | 2017-10-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis.
Nucleic Acids Res., 45, 2017
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5LTW
 | | Complex of human 14-3-3 sigma CLU1 mutant with phosphorylated heat shock protein B6 | | Descriptor: | 14-3-3 protein sigma, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heat shock protein beta-6, ... | | Authors: | Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V. | | Deposit date: | 2016-09-07 | | Release date: | 2017-02-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
Structure, 25, 2017
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5LU2
 | | Human 14-3-3 sigma complexed with long HSPB6 phosphopeptide | | Descriptor: | 14-3-3 protein sigma, Heat shock protein beta-6 | | Authors: | Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V. | | Deposit date: | 2016-09-07 | | Release date: | 2017-02-01 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
Structure, 25, 2017
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5OEA
 | | Structure of large terminase from the thermophilic bacteriophage D6E in complex with ATP-gamma-S (Crystal form 3) | | Descriptor: | Large subunit terminase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Xu, R.G, Jenkins, H.T, Greive, S.J, Antson, A.A. | | Deposit date: | 2017-07-07 | | Release date: | 2017-10-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis.
Nucleic Acids Res., 45, 2017
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5OEE
 | | Structure of large terminase from the thermophilic bacteriophage D6E (Crystal form 3) | | Descriptor: | Large subunit terminase, SODIUM ION | | Authors: | Xu, R.G, Jenkins, H.T, Greive, S.J, Antson, A.A. | | Deposit date: | 2017-07-07 | | Release date: | 2017-10-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis.
Nucleic Acids Res., 45, 2017
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