5Z7D
| p204HINab-dsDNA complex structure | Descriptor: | DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204 | Authors: | Jin, T, Jiang, J, Xiao, T.S. | Deposit date: | 2018-01-28 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res., 2021
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7E2M
| Crystal structure of the RWD domain of human GCN2 - 2 | Descriptor: | eIF-2-alpha kinase GCN2 | Authors: | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | Deposit date: | 2021-02-05 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2. Biochem.Biophys.Res.Commun., 549, 2021
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4UIH
| Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. | Deposit date: | 2015-03-30 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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5ITX
| Crystal Structure of Human NEIL1(P2G R242K) bound to duplex DNA containing Thymine Glycol | Descriptor: | DNA (26-MER), Endonuclease 8-like 1 | Authors: | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | Deposit date: | 2016-03-17 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair Proc.Natl.Acad.Sci.USA, 113, 2016
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7ETS
| Crystal structure of crp protein from Gardnerella Vaginalis | Descriptor: | Crp/Fnr family transcriptional regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Dong, H.J, Wang, S, Zhang, J.M, Gu, L. | Deposit date: | 2021-05-13 | Release date: | 2022-04-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal structure of crp protein from Gardnerella Vaginalis To Be Published
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6JG0
| Crystal structure of the N-terminal domain single mutant (S92E) of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Endolysin,Calcium uniporter protein, SULFATE ION | Authors: | Lee, Y, Park, J, Min, C.K, Kang, J.Y, Kim, T.G, Yamamoto, T, Kim, D.H, Eom, S.H. | Deposit date: | 2019-02-13 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of calcium channel domain To Be Published
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5Z6P
| The crystal structure of an agarase, AgWH50C | Descriptor: | B-agarase | Authors: | Mao, X, Zhou, J, Zhang, P, Zhang, L, Zhang, J, Li, Y. | Deposit date: | 2018-01-24 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.061 Å) | Cite: | Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability. Appl. Microbiol. Biotechnol., 103, 2019
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8WKX
| Cryo-EM structure of DSR2 | Descriptor: | SIR2-like domain-containing protein | Authors: | Gao, A, Huang, J, Zhu, K. | Deposit date: | 2023-09-28 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion. Nat Commun, 15, 2024
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5ITY
| Crystal Structure of Human NEIL1(P2G) bound to duplex DNA containing Thymine Glycol | Descriptor: | DNA (26-MER), Endonuclease 8-like 1, GLYCEROL | Authors: | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | Deposit date: | 2016-03-17 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair Proc.Natl.Acad.Sci.USA, 113, 2016
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8WKS
| Cryo-EM structure of DSR2-TUBE complex | Descriptor: | SIR2-like domain-containing protein, TUBE | Authors: | Gao, A, Huang, J, Zhu, K. | Deposit date: | 2023-09-28 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion. Nat Commun, 15, 2024
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8WKT
| Cryo-EM structure of DSR2-DSAD1 complex | Descriptor: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | Authors: | Gao, A, Huang, J, Zhu, K. | Deposit date: | 2023-09-28 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion. Nat Commun, 15, 2024
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2UZK
| Crystal structure of the human FOXO3a-DBD bound to DNA | Descriptor: | 5'-D(*CP*TP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*AP*G)-3', FORKHEAD BOX PROTEIN O3A | Authors: | Tsai, K.-L, Sun, Y.-J, Huang, C.-Y, Yang, J.-Y, Hung, M.-C, Hsiao, C.-D. | Deposit date: | 2007-04-30 | Release date: | 2008-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of the Human Foxo3A-Dbd/DNA Complex Suggests the Effects of Post-Translational Modification. Nucleic Acids Res., 35, 2007
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8XH7
| Structure of EBV LMP1 oligomer | Descriptor: | Latent membrane protein 1 | Authors: | Gao, P, Huang, J.F. | Deposit date: | 2023-12-17 | Release date: | 2024-06-26 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Assembly and activation of EBV latent membrane protein 1. Cell, 2024
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7KKJ
| Structure of anti-SARS-CoV-2 Spike nanobody mNb6 | Descriptor: | CHLORIDE ION, SULFATE ION, Synthetic nanobody mNb6 | Authors: | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | Deposit date: | 2020-10-27 | Release date: | 2020-11-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science, 370, 2020
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8XH6
| Structure of EBV LMP1 dimer | Descriptor: | Latent membrane protein 1 | Authors: | Gao, P, Huang, J.F. | Deposit date: | 2023-12-17 | Release date: | 2024-06-26 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Assembly and activation of EBV latent membrane protein 1. Cell, 2024
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7F6W
| Crystal structure of Saccharomyces cerevisiae lysyl-tRNA Synthetase | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine--tRNA ligase | Authors: | Wu, S, Li, P, Hei, Z, Zheng, L, Wang, J, Fang, P. | Deposit date: | 2021-06-26 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.607 Å) | Cite: | Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex. Cell.Mol.Life Sci., 79, 2022
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7KKK
| SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | Deposit date: | 2020-10-27 | Release date: | 2020-11-11 | Last modified: | 2021-04-21 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science, 370, 2020
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2H2K
| Crystal Structure Analysis of Human S100A13 | Descriptor: | CALCIUM ION, Protein S100-A13 | Authors: | Li, M, Zhang, P.F, Zhang, J.P, Chang, W.R. | Deposit date: | 2006-05-19 | Release date: | 2007-05-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure study on human S100A13 at 2.0 A resolution Biochem.Biophys.Res.Commun., 356, 2007
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3BN3
| crystal structure of ICAM-5 in complex with aL I domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Zhang, H, Springer, T.A, Wang, J.-h. | Deposit date: | 2007-12-13 | Release date: | 2008-08-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | An unusual allosteric mobility of the C-terminal helix of a high-affinity alpha L integrin I domain variant bound to ICAM-5 Mol.Cell, 31, 2008
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5DQC
| Co-crystal of BACE1 with compound 0211 | Descriptor: | Beta-secretase 1, N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | Authors: | Ghosh, A.K, Bhavanam, S.R, Yen, T.-C, Cardenas, E.L, Rao, K.V, Downs, D, Huang, X, Tang, J, Mescar, A.D. | Deposit date: | 2015-09-14 | Release date: | 2016-02-17 | Last modified: | 2016-07-13 | Method: | X-RAY DIFFRACTION (2.4651 Å) | Cite: | Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes. Chem Sci, 7, 2016
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7F7O
| APC-Asef FP assay tracer | Descriptor: | Adenomatous polyposis coli protein, N-[3',6'-bis(oxidanyl)-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-5-yl]methanethioamide, Tracer 7 | Authors: | Yang, X, Zhang, J. | Deposit date: | 2021-06-30 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The tracer of FP assay for screening APC-Asef inhbitors To Be Published
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2MLB
| NMR solution structure of a computational designed protein based on template of human erythrocytic ubiquitin | Descriptor: | redesigned ubiquitin | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-02-21 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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2MN4
| NMR solution structure of a computational designed protein based on structure template 1cy5 | Descriptor: | Computational designed protein based on structure template 1cy5 | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-03-28 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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2NAS
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4F5W
| Crystal structure of ligand free human STING CTD | Descriptor: | CALCIUM ION, Transmembrane protein 173 | Authors: | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | Deposit date: | 2012-05-13 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP Nat.Struct.Mol.Biol., 19, 2012
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