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PDB: 119 results

6HMI
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BU of 6hmi by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
Descriptor: RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Allain, F.H.
Deposit date:2018-09-12
Release date:2019-08-14
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
5OR5
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BU of 5or5 by Molmil
NMR structure of the complex formed by an engineered region 2 of sigmaE in complex with GTAAAA
Descriptor: DNA (5'-D(*GP*TP*AP*AP*AP*A)-3'), ECF RNA polymerase sigma-E factor,ECF RNA polymerase sigma factor SigW,ECF RNA polymerase sigma-E factor
Authors:Campagne, S, Vorholt, J.A, Allain, F.H.
Deposit date:2017-08-15
Release date:2018-06-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Engineered promoter selectivity of an ECF sigma factor
Not published
4ZKA
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BU of 4zka by Molmil
High Resolution Crystal Structure of Fox1 RRM
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, RNA binding protein fox-1 homolog 1, SULFATE ION, ...
Authors:Blatter, M, Allain, F.H.-T.
Deposit date:2015-04-30
Release date:2016-06-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High Resolution Crystal Structure of Fox1 RRM
To Be Published
6SNJ
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BU of 6snj by Molmil
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Descriptor: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
Authors:Campagne, S, Allain, F.H.
Deposit date:2019-08-26
Release date:2020-10-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
2ADC
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BU of 2adc by Molmil
Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1
Authors:Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T.
Deposit date:2005-07-20
Release date:2005-10-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
2AD9
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BU of 2ad9 by Molmil
Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA
Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1
Authors:Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T.
Deposit date:2005-07-20
Release date:2005-10-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
5OR0
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BU of 5or0 by Molmil
NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA
Descriptor: RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Clery, A, Allain, F.H.
Deposit date:2017-08-14
Release date:2017-08-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Nat Commun, 8, 2017
2ADB
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BU of 2adb by Molmil
Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA
Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1
Authors:Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T.
Deposit date:2005-07-20
Release date:2005-10-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
7QDD
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BU of 7qdd by Molmil
NMR structure of Npl3 RRM1 bound to the AUCCAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*A)-3')
Authors:Clery, A, Allain, F.H.-T, Moursy, A.
Deposit date:2021-11-26
Release date:2022-10-26
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023
7ZAP
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BU of 7zap by Molmil
Solution structure of RBM39 RRM1 bound to U1 snRNA stem loop 3
Descriptor: RNA-binding protein 39, U1 snRNA SL3
Authors:Campagne, S, Allain, F.H.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-09-20
Method:SOLUTION NMR
Cite:Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
1IE2
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BU of 1ie2 by Molmil
Solution Structure of an In Vitro Selected RNA which is Sequence Specifically Recognized by RBD12 of Hamster Nucleolin.sNRE (anti)
Descriptor: 5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*UP*CP*CP*CP*GP*AP*AP*GP*UP*AP*GP*GP*CP*C)-3'
Authors:Bouvet, P, Allain, F.H.-T, Finger, L.D, Dieckmann, T, Feigon, J.
Deposit date:2001-04-05
Release date:2001-06-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin.
J.Mol.Biol., 309, 2001
1IE1
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BU of 1ie1 by Molmil
NMR Solution Structure of an In Vitro Selected RNA which is Sequence Specifically Recognized by Hamster Nucleolin RBD12.
Descriptor: 5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*UP*CP*CP*CP*GP*AP*AP*GP*UP*AP*GP*GP*CP*C)-3'
Authors:Bouvet, P, Allain, F.H.-T, Finger, L.D, Dieckmann, T, Feigon, J.
Deposit date:2001-04-05
Release date:2001-06-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin.
J.Mol.Biol., 309, 2001
1J5N
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BU of 1j5n by Molmil
Solution Structure of the Non-Sequence-Specific HMGB protein NHP6A in complex with SRY DNA
Descriptor: 5'-D(*CP*TP*GP*AP*AP*CP*AP*AP*TP*CP*AP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*TP*GP*AP*TP*TP*GP*TP*TP*CP*AP*G)-3', Nonhistone chromosomal protein 6A
Authors:Masse, J.E, Wong, B, Yen, Y.-M, Allain, F.H.-T, Johnson, R.C, Feigon, J.
Deposit date:2002-05-15
Release date:2002-10-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding
J.Mol.Biol., 323, 2002
7Q4L
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BU of 7q4l by Molmil
The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA
Descriptor: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3')
Authors:Duszczyk, M.M, Allain, F.H.T.
Deposit date:2021-10-31
Release date:2022-05-04
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
Nat Commun, 13, 2022
4B0R
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BU of 4b0r by Molmil
Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway
Descriptor: DEAMIDASE-DEPUPYLASE DOP
Authors:Ozcelik, D, Barandun, J, Schmitz, N, Sutter, M, Guth, E, Damberger, F.F, Allain, F.H.-T, Ban, N, Weber-Ban, E.
Deposit date:2012-07-04
Release date:2012-09-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathway.
Nat Commun, 3, 2012
1LWM
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BU of 1lwm by Molmil
Solution Structure of the Sequence-Non-Specific HMGB protein NHP6A
Descriptor: NONHISTONE CHROMOSOMAL PROTEIN 6A
Authors:Masse, J.E, Wong, B, Yen, Y.-M, Allain, F.H.-T, Johnson, R.C, Feigon, J.
Deposit date:2002-05-31
Release date:2002-10-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding
J.Mol.Biol., 323, 2002
7Q33
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BU of 7q33 by Molmil
Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3
Descriptor: RNA (5'-R(*AP*GP*CP*UP*UP*UP*G)-3'), RNA-binding protein 39
Authors:Campagne, S, Allain, F.H.
Deposit date:2021-10-26
Release date:2023-02-08
Last modified:2023-09-20
Method:SOLUTION NMR
Cite:Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
4BS2
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BU of 4bs2 by Molmil
NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA
Descriptor: 5'-R(*GP*UP*GP*UP*GP*AP*AP*UP*GP*AP*AP*UP)-3', TAR DNA-BINDING PROTEIN 43
Authors:Lukavsky, P.J, Daujotyte, D, Tollervey, J.R, Ule, J, Stuani, C, Buratti, E, Baralle, F.E, Damberger, F.F, Allain, F.H.T.
Deposit date:2013-06-06
Release date:2013-11-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular Basis of Ug-Rich RNA Recognition by the Human Splicing Factor Tdp-43
Nat.Struct.Mol.Biol., 20, 2013
5M8I
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BU of 5m8i by Molmil
Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA
Descriptor: CUGBP Elav-like family member 2, RNA (5'-R(*UP*UP*UP*AP*A)-3')
Authors:Diarra dit Konte, N, Damberger, F.F, Allain, F.H.T.
Deposit date:2016-10-28
Release date:2017-10-11
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Nat Commun, 8, 2017
5MPL
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BU of 5mpl by Molmil
hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UCAGUU
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
5MPG
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BU of 5mpg by Molmil
Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UUAGGUC
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
1YSV
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BU of 1ysv by Molmil
Solution structure of the central region of the human GluR-B R/G pre-mRNA
Descriptor: 27-MER
Authors:Stefl, R, Allain, F.H.
Deposit date:2005-02-09
Release date:2005-07-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel RNA pentaloop fold involved in targeting ADAR2.
Rna, 11, 2005
4B0T
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BU of 4b0t by Molmil
Structure of the Pup Ligase PafA of the Prokaryotic Ubiquitin-like Modification Pathway in Complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PUP--PROTEIN LIGASE
Authors:Ozcelik, D, Barandun, J, Schmitz, N, Sutter, M, Guth, E, Damberger, F.F, Allain, F.H.-T, Ban, N, Weber-Ban, E.
Deposit date:2012-07-04
Release date:2012-09-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.159 Å)
Cite:Structures of Pup Ligase Pafa and Depupylase Dop from the Prokaryotic Ubiquitin-Like Modification Pathway.
Nat.Commun., 3, 2012
4B0S
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BU of 4b0s by Molmil
Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway in Complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DEAMIDASE-DEPUPYLASE DOP, MAGNESIUM ION
Authors:Ozcelik, D, Barandun, J, Schmitz, N, Sutter, M, Guth, E, Damberger, F.F, Allain, F.H.-T, Ban, N, Weber-Ban, E.
Deposit date:2012-07-04
Release date:2012-09-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Pup Ligase Pafa and Depupylase Dop from the Prokaryotic Ubiquitin-Like Modification Pathway.
Nat.Commun., 3, 2012
1YNE
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BU of 1yne by Molmil
NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor
Descriptor: APOLIPOPROTEIN B mRNA
Authors:Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N.
Deposit date:2005-01-24
Release date:2005-02-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor.
Rna, 11, 2005

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