3OUS
| MthK channel pore T59A mutant | 分子名称: | Calcium-gated potassium channel mthK, POTASSIUM ION | 著者 | Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y. | 登録日 | 2010-09-15 | 公開日 | 2011-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proc.Natl.Acad.Sci.USA, 108, 2011
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2AHY
| Na+ complex of the NaK Channel | 分子名称: | CALCIUM ION, Potassium channel protein, SODIUM ION | 著者 | Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y. | 登録日 | 2005-07-28 | 公開日 | 2006-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Atomic structure of a Na+- and K+-conducting channel. Nature, 440, 2006
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2AHZ
| K+ complex of the NaK Channel | 分子名称: | CALCIUM ION, POTASSIUM ION, Potassium channel protein | 著者 | Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y. | 登録日 | 2005-07-28 | 公開日 | 2006-02-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Atomic structure of a Na+- and K+-conducting channel. Nature, 440, 2006
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2A20
| Solution structure of Rim2 Zinc Finger Domain | 分子名称: | Regulating synaptic membrane exocytosis protein 2, ZINC ION | 著者 | Dulubova, I, Lou, X, Lu, J, Huryeva, I, Alam, A, Schneggenburger, R, Sudhof, T.C, Rizo, J. | 登録日 | 2005-06-21 | 公開日 | 2005-08-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? Embo J., 24, 2005
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4B2D
| human PKM2 with L-serine and FBP bound. | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PYRUVATE KINASE ISOZYMES M1/M2, ... | 著者 | Chaneton, B, Hillmann, P, Zheng, L, Martin, A.C.L, Maddocks, O.D.K, Chokkathukalam, A, Coyle, J.E, Jankevics, A, Holding, F.P, Vousden, K.H, Frezza, C, O'Reilly, M, Gottlieb, E. | 登録日 | 2012-07-13 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Serine is a natural ligand and allosteric activator of pyruvate kinase M2. Nature, 491, 2012
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6GZM
| Crystal Structure of Human CKIdelta with A86 | 分子名称: | CITRIC ACID, Casein kinase I isoform delta, GLYCEROL, ... | 著者 | Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. | 登録日 | 2018-07-04 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
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6GZD
| Crystal structure of Human CSNK1A1 with A86 | 分子名称: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Casein kinase I isoform alpha, ... | 著者 | Ben-Neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. | 登録日 | 2018-07-03 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
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6GZH
| Crystal Structure of Human CDK9/cyclinT1 with A86 | 分子名称: | Cyclin-T1, Cyclin-dependent kinase 9, GLYCEROL, ... | 著者 | Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. | 登録日 | 2018-07-04 | 公開日 | 2018-08-29 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
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8PJ8
| FKBP51FK1 F67E/K60Orn (i, i+7) in complex with SAFit1 | 分子名称: | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid, Peptidyl-prolyl cis-trans isomerase FKBP5 | 著者 | Meyners, C, Charalampidou, A, Hausch, F. | 登録日 | 2023-06-23 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets. Acs Cent.Sci., 10, 2024
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8PJA
| FKBP51FK1 F67E/K58 (i, i+9) in complex with SAFit1 | 分子名称: | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid, Peptidyl-prolyl cis-trans isomerase FKBP5 | 著者 | Meyners, C, Charalampidou, A, Hausch, F. | 登録日 | 2023-06-23 | 公開日 | 2024-03-06 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets. Acs Cent.Sci., 10, 2024
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1O8C
| CRYSTAL STRUCTURE OF E. COLI K-12 YHDH WITH BOUND NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, YHDH | 著者 | Sulzenbacher, G, Roig-Zamboni, V, Pagot, F, Grisel, S, Salamoni, A, Valencia, C, Bignon, C, Vincentelli, R, Tegoni, M, Cambillau, C. | 登録日 | 2002-11-26 | 公開日 | 2004-05-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Escherichia Coli Yhdh, a Putative Quinone Oxidoreductase Acta Crystallogr.,Sect.D, 60, 2004
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1O89
| Crystal structure of E. COLI K-12 yhdH | 分子名称: | YHDH | 著者 | Sulzenbacher, G, Roig-Zamboni, V, Pagot, F, Grisel, S, Salamoni, A, Valencia, C, Bignon, C, Vincentelli, R, Tegoni, M, Cambillau, C. | 登録日 | 2002-11-26 | 公開日 | 2004-02-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Escherichia Coli Yhdh, a Putative Quinone Oxidoreductase Acta Crystallogr.,Sect.D, 60, 2004
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1OJ7
| STRUCTURAL GENOMICS, UNKNOWN FUNCTION CRYSTAL STRUCTURE OF E. COLI K-12 YQHD | 分子名称: | 5,6-DIHYDROXY-NADP, BORIC ACID, CHLORIDE ION, ... | 著者 | Sulzenbacher, G, Perrier, S, Roig-Zamboni, V, Pagot, F, Grisel, S, Salamoni, A, Valencia, C, Bignon, C, Vincentelli, R, Tegoni, M, Cambillau, C. | 登録日 | 2003-07-03 | 公開日 | 2004-07-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of E.Coli Alcohol Dehydrogenase Yqhd: Evidence of a Covalently Modified Nadp Coenzyme J.Mol.Biol., 342, 2004
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